Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | IGF1R | P08069 | 2/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | INSR | P06213 | 1/20 | 0.38 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | TEK | Q02763 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7678516 | 0.87 | FAAH (0.42) | MEN1KMT2AIGF1REGFRINSR | |
| SCHEMBL7670964 | 0.83 | MEN1 (0.45) | MEN1KMT2AKDRKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL7672407 | 0.82 | MEN1 (0.44) | MEN1KMT2AKDRKDM4EALDH1A1 | |
| SCHEMBL7671243 | 0.82 | MEN1 (0.44) | MEN1KMT2AKDRKDM4EALDH1A1 | |
| SCHEMBL7678998 | 0.82 | MEN1 (0.43) | MEN1KMT2AKDRKDM4EALDH1A1 | |
| SCHEMBL7675359 | 0.82 | MEN1 (0.43) | MEN1KMT2AKDRKDM4EALDH1A1 | |
| SCHEMBL7679446 | 0.80 | MEN1 (0.46) | MEN1KMT2AKDRKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL7677732 | 0.80 | MEN1 (0.45) | MEN1KMT2AKDRKDM4EALDH1A1 | |
| SCHEMBL7672108 | 0.79 | DRD3 (0.41) | DRD2DRD3CYP1A2CYP2D6KDM4E | |
| SCHEMBL7677729 | 0.77 | KDR (0.35) | IGF1REGFRINSRMETCDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6479514-B1 | FOR THE CONTROL OF HELICOBACTER BACTERIA IN INFECTED PATIENTS | ALTANA PHARMA AG (DE) | 2002-11-12 | — | — | US | disclosed |
| EP-1086094-A1 | QUINOLINE-AMINOMETHYL-PYRIDYL DERIVATIVES WITH ANTI-HELICOBACTER ACTIVITY | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 2001-03-28 | — | — | EP | disclosed |
| WO-1999061438-A1 | QUINOLINE-AMINOMETHYL-PYRIDYL DERIVATIVES WITH ANTI-HELICOBACTER ACTIVITY | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1999-12-02 | — | — | WO | disclosed |