Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.57 |
| ▸ | MAOA | P21397 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | F12 | P00748 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | F2 | P00734 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7680586 | 0.81 | F2 (0.70) | MAOBCA12CA9KMT2AMEN1 | |
| SCHEMBL27951961 | 0.77 | CA12 (0.74) | MAOBMAOAPOLBCA12CA9 | |
| SCHEMBL7678743 | 0.75 | MEN1 (0.58) | MAOBMAOAPOLBCA12CA9 | |
| SCHEMBL31206250 | 0.75 | MAOB (0.77) | MAOBMAOAPOLBCA12CA9 | |
| SCHEMBL11481128 | 0.75 | MAOB (0.77) | MAOBMAOAPOLBCA12CA9 | |
| SCHEMBL1369655 | 0.75 | MAOB (0.81) | MAOBMAOAPOLBCA12CA9 | |
| SCHEMBL30595105 | 0.74 | CA12 (0.69) | MAOBMAOAPOLBCA12CA9 | |
| SCHEMBL7672880 | 0.74 | CA12 (0.69) | MAOBMAOAPOLBCA12CA9 | |
| SCHEMBL5717527 | 0.73 | MAOB (1.00) | MAOBMAOAPOLBCA12CA9 | |
| SCHEMBL5190662 | 0.72 | POLB (1.00) | MAOBMAOAPOLBCA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6355658-B1 | COUMARIN ESTERS WITH ETHER GROUPS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2002-03-12 | — | — | US | disclosed |