Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | MAOB | P27338 | 7/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | HPGD | P15428 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | GAA | P10253 | 3/20 | 0.57 |
| ▸ | GLA | P06280 | 2/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | CA3 | P07451 | 1/20 | 0.57 |
| ▸ | CA4 | P22748 | 1/20 | 0.57 |
| ▸ | CA6 | P23280 | 1/20 | 0.57 |
| ▸ | CA7 | P43166 | 1/20 | 0.57 |
| ▸ | CA9 | Q16790 | 1/20 | 0.57 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.57 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.57 |
| ▸ | MAOA | P21397 | 4/20 | 0.57 |
| ▸ | F12 | P00748 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7681924 | 0.78 | POLB (0.63) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL6687148 | 0.78 | MAOB (0.76) | MAOBALDH1A1HPGDKDM4EGAA | |
| SCHEMBL7680586 | 0.77 | F2 (0.70) | MEN1KMT2AMAOBCA12CA2 | |
| SCHEMBL11829416 | 0.75 | ALDH1A1 (0.76) | MEN1KMT2AMAOBALDH1A1HPGD | |
| SCHEMBL7678609 | 0.75 | MAOB (0.57) | MEN1KMT2AMAOBALDH1A1KDM4E | |
| SCHEMBL1366230 | 0.75 | ALDH1A1 (0.81) | MEN1KMT2AMAOBALDH1A1HPGD | |
| SCHEMBL52650 | 0.75 | ALDH1A1 (0.81) | MEN1KMT2AMAOBALDH1A1HPGD | |
| SCHEMBL18382590 | 0.75 | MAOB (0.79) | KMT2AMAOBALDH1A1HPGDKDM4E | |
| SCHEMBL203997 | 0.74 | SLC16A3 (1.00) | KMT2AMAOBALDH1A1HPGDKDM4E | |
| SCHEMBL1104931 | 0.74 | ALDH1A1 (1.00) | MEN1KMT2AMAOBALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6355658-B1 | COUMARIN ESTERS WITH ETHER GROUPS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2002-03-12 | — | — | US | disclosed |