Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | AXL | P30530 | 1/20 | 0.35 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.35 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.35 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.35 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.35 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.35 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.35 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6949924 | 0.73 | CCNE1 (0.35) | KMT2AMAPK14TDP1MAPK13MAPK12 | |
| SCHEMBL6742425 | 0.72 | THRB (0.38) | KDM4EKMT2AMAPK14TDP1ALDH1A1 | |
| SCHEMBL7681334 | 0.69 | EPHX1 (0.48) | KDM4EKMT2AALDH1A1LMNAPOLB | |
| SCHEMBL9845318 | 0.69 | LCK (0.57) | HDAC1HDAC6KMT2AMAPK14MAPK13 | |
| SCHEMBL5423478 | 0.65 | KDM4E (0.72) | KDM4EHDAC1HDAC6KMT2ATDP1 | |
| SCHEMBL27320443 | 0.64 | NPSR1 (0.50) | KDM4EHDAC1HDAC6KMT2AALDH1A1 | |
| SCHEMBL9845322 | 0.64 | HDAC1 (0.60) | KDM4EHDAC1HDAC6KMT2AALDH1A1 | |
| SCHEMBL7680123 | 0.64 | THRB (0.38) | KDM4EKMT2AMAPK14TDP1ALDH1A1 | |
| SCHEMBL5431621 | 0.62 | KDM4E (0.67) | KDM4EHDAC1HDAC6KMT2ATDP1 | |
| SCHEMBL5426967 | 0.62 | KDM4E (0.76) | KDM4EHDAC1HDAC6KMT2AMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6472349-B1 | Pyridine-2,3-dicarboxylic acid diamides | BASF AKTIENGESELLSCHAFT (DE) | 2002-10-29 | — | — | US | disclosed |