Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.36 |
| ▸ | PDE4A | P27815 | 2/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7680123 | 0.92 | THRB (0.38) | THRBRECQLPOLBTDP1L3MBTL1 | |
| SCHEMBL6949924 | 0.85 | CCNE1 (0.35) | THRBRECQLPOLBTDP1L3MBTL1 | |
| SCHEMBL7682613 | 0.85 | PDE4D (0.44) | THRBRECQLPOLBTDP1L3MBTL1 | |
| SCHEMBL6735881 | 0.84 | POLB (0.38) | THRBRECQLPOLBTDP1L3MBTL1 | |
| SCHEMBL7680208 | 0.82 | PDE4A (0.38) | THRBRECQLPOLBTDP1L3MBTL1 | |
| SCHEMBL7685867 | 0.80 | PDE4B (0.36) | THRBRECQLPOLBTDP1L3MBTL1 | |
| SCHEMBL7683047 | 0.80 | PDE4A (0.38) | THRBRECQLPOLBTDP1L3MBTL1 | |
| SCHEMBL7679361 | 0.79 | PDE4B (0.38) | THRBRECQLPOLBTDP1L3MBTL1 | |
| SCHEMBL7676323 | 0.78 | PDE4A (0.39) | THRBRECQLPOLBTDP1L3MBTL1 | |
| SCHEMBL7676345 | 0.77 | ALDH1A1 (0.38) | ALDH1A1MAPK14CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6683213-B1 | CHEMICAL INTERMEDIATES FOR PYRIDINEDICARBOXAMIDE HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2004-01-27 | — | — | US | disclosed |
| US-6472349-B1 | Pyridine-2,3-dicarboxylic acid diamides | BASF AKTIENGESELLSCHAFT (DE) | 2002-10-29 | — | — | US | disclosed |