Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 2/20 | 0.35 |
| ▸ | CDK2 | P24941 | 2/20 | 0.35 |
| ▸ | PDE4A | P27815 | 2/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.34 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.34 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7464085 | 0.86 | PDE4D (0.42) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL6949794 | 0.85 | HDAC1 (0.36) | CCNE1CDK2PDE4APDE4BPDE4C | |
| SCHEMBL6742425 | 0.85 | THRB (0.38) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL7456776 | 0.84 | PDE4A (0.37) | CCNE1CDK2PDE4APDE4BPDE4C | |
| SCHEMBL7458253 | 0.80 | PDE4A (0.38) | CCNE1CDK2PDE4APDE4BPDE4C | |
| SCHEMBL7460856 | 0.78 | PDE4A (0.36) | CCNE1CDK2PDE4APDE4BPDE4C | |
| SCHEMBL7680123 | 0.77 | THRB (0.38) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL7678741 | 0.73 | KDM4E (0.39) | ALDH1A1LMNAPOLBTDP1L3MBTL1 | |
| SCHEMBL7460958 | 0.73 | GAA (0.40) | CCNE1CDK2ALDH1A1ITGB1ITGA4 | |
| SCHEMBL7682613 | 0.72 | PDE4D (0.44) | PDE4APDE4BPDE4CPDE4DALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165496-B1 | SUBSTITUTED ANILINE COMPOUNDS | BASF AG (DE) | 2003-07-09 | — | — | EP | disclosed |