Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 7/20 | 1.00 |
| ▸ | CA6 | P23280 | 7/20 | 1.00 |
| ▸ | CA7 | P43166 | 7/20 | 1.00 |
| ▸ | CA9 | Q16790 | 7/20 | 1.00 |
| ▸ | CA14 | Q9ULX7 | 7/20 | 1.00 |
| ▸ | CA5B | Q9Y2D0 | 7/20 | 1.00 |
| ▸ | CA2 | P00918 | 6/20 | 1.00 |
| ▸ | CA3 | P07451 | 6/20 | 1.00 |
| ▸ | CA4 | P22748 | 5/20 | 1.00 |
| ▸ | CA1 | P00915 | 4/20 | 1.00 |
| ▸ | CA5A | P35218 | 5/20 | 0.70 |
| ▸ | MAOA | P21397 | 2/20 | 0.65 |
| ▸ | GPR35 | Q9HC97 | 7/20 | 0.63 |
| ▸ | MAOB | P27338 | 3/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.63 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.63 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.63 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14326443 | 0.88 | CA12 (0.78) | CA12CA6CA7CA9CA14 | |
| SCHEMBL11507962 | 0.86 | CA12 (0.76) | CA12CA6CA7CA9CA14 | |
| SCHEMBL8209413 | 0.86 | CA12 (0.76) | CA12CA6CA7CA9CA14 | |
| SCHEMBL7680121 | 0.86 | CA12 (0.76) | CA12CA6CA7CA9CA14 | |
| SCHEMBL8208616 | 0.81 | CA12 (0.68) | CA12CA6CA7CA9CA14 | |
| SCHEMBL14652705 | 0.81 | F2 (0.80) | CA12CA6CA7CA9CA14 | |
| SCHEMBL7678492 | 0.80 | CA12 (1.00) | CA12CA6CA7CA9CA14 | |
| SCHEMBL8208896 | 0.79 | CA12 (0.65) | CA12CA6CA7CA9CA14 | |
| SCHEMBL11266285 | 0.79 | MAOA (0.71) | CA12CA6CA7CA9CA14 | |
| SCHEMBL979779 | 0.79 | MAOA (1.00) | CA12CA6CA7CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023213728-A1 | SUBSTITUTED ARYL ESTERS OF COUMARIN-3-CARBOXYLIC ACID AND THEIR USE AS HOST CELL PROTEASES INHIBITORS | Université de Liège (BE) | 2023-11-09 | — | — | WO | disclosed |
| WO-2023213728-A1 | SUBSTITUTED ARYL ESTERS OF COUMARIN-3-CARBOXYLIC ACID AND THEIR USE AS HOST CELL PROTEASES INHIBITORS | Université de Liège (BE) | 2023-11-09 | — | — | WO | disclosed |
| US-6355658-B1 | COUMARIN ESTERS WITH ETHER GROUPS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2002-03-12 | — | — | US | disclosed |
| EP-0988298-A1 | COUMARIN DERIVATIVES, METHODS OF PREPARATION AND APPLICATION AS MEDICINES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2000-03-29 | — | — | EP | disclosed |
| WO-1998055472-A1 | COUMARIN DERIVATIVES, METHODS OF PREPARATION AND APPLICATION AS MEDICINES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 1998-12-10 | — | — | WO | disclosed |