Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 3/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.37 |
| ▸ | GRIK1 | P39086 | 3/20 | 0.34 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.34 |
| ▸ | CES2 | O00748 | 2/20 | 0.33 |
| ▸ | CES1 | P23141 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | EP300 | Q09472 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2521628 | 0.88 | APEX1 (0.39) | GRIK1CES2CES1TSHRFAAH | |
| SCHEMBL4791448 | 0.88 | APEX1 (0.39) | GRIK1CES2CES1TSHRFAAH | |
| SCHEMBL7677056 | 0.86 | AKR1B1 (0.43) | CES2CES1TSHRFAAHEP300 | |
| SCHEMBL7674491 | 0.85 | TSHR (0.46) | TSHRFAAHEP300ALDH1A1 | |
| SCHEMBL1843576 | 0.85 | TSHR (0.46) | TSHRFAAHEP300ALDH1A1 | |
| SCHEMBL2522759 | 0.83 | ALDH1A1 (0.37) | FFAR3GRIK1GRIK2TSHRALDH1A1 | |
| SCHEMBL7679064 | 0.83 | ALDH1A1 (0.37) | FFAR3GRIK1GRIK2TSHRALDH1A1 | |
| Butane SCHEMBL10765613 | 0.82 | GRIK1 (0.33) | GRIK1GRIK2TSHRFAAHEP300 | |
| Propane SCHEMBL15303565 | 0.79 | GRIK1 (0.32) | GRIK1GRIK2TSHRALDH1A1 | |
| SCHEMBL9493661 | 0.78 | GRIK1 (0.50) | FFAR3HDAC3HDAC1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6448340-B1 | CORE OR INTERMEDIATE LAYER FORMED OF BLEND OF HIGH ACID AND VERY LOW MUODULUS IONOMER (VLMI) RESINS; IMPROVED INITIAL VELOCITY AND RESILENCE | JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT | 2002-09-10 | — | — | US | claimed |