Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 8/20 | 0.45 |
| ▸ | PPARD | Q03181 | 8/20 | 0.45 |
| ▸ | PPARA | Q07869 | 8/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | FABP4 | P15090 | 3/20 | 0.45 |
| ▸ | TLR2 | O60603 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.45 |
| ▸ | FABP3 | P05413 | 2/20 | 0.45 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.45 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1843576 | 1.00 | TSHR (0.46) | TSHRFAAHPPARGPPARDPPARA | |
| SCHEMBL7677056 | 0.98 | AKR1B1 (0.43) | TSHRFAAHPPARGPPARDPPARA | |
| SCHEMBL2521628 | 0.93 | APEX1 (0.39) | TSHRFAAHPPARGPPARDPPARA | |
| SCHEMBL4791448 | 0.93 | APEX1 (0.39) | TSHRFAAHPPARGPPARDPPARA | |
| SCHEMBL7679499 | 0.85 | FFAR3 (0.37) | TSHRFAAHALDH1A1EP300 | |
| SCHEMBL2909571 | 0.84 | EP300 (0.46) | TSHRFAAHPPARGPPARDPPARA | |
| SCHEMBL16594756 | 0.83 | TSHR (0.53) | TSHRFAAHPPARGPPARDPPARA | |
| Acrylic Acid SCHEMBL277786 | 0.82 | GPR84 (0.45) | TSHRFAAHPPARGPPARDPPARA | |
| SCHEMBL1076720 | 0.82 | FAAH (0.42) | TSHRFAAHPPARGPPARDPPARA | |
| SCHEMBL1077289 | 0.82 | FAAH (0.42) | TSHRFAAHPPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6448340-B1 | CORE OR INTERMEDIATE LAYER FORMED OF BLEND OF HIGH ACID AND VERY LOW MUODULUS IONOMER (VLMI) RESINS; IMPROVED INITIAL VELOCITY AND RESILENCE | JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT | 2002-09-10 | — | — | US | claimed |