Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | SI | P14410 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6373056 | 0.87 | TSHR (0.53) | ALDH1A1LMNATSHRGAAMGAM | |
| SCHEMBL5096848 | 0.82 | ALDH1A1 (0.47) | ALDH1A1LMNATSHRMAPTL3MBTL1 | |
| SCHEMBL11020276 | 0.82 | ALDH1A1 (0.57) | ALDH1A1LMNATSHRMAPTCES2 | |
| SCHEMBL11385468 | 0.80 | POLB (0.46) | ALDH1A1LMNATSHRMAPTRAB9A | |
| SCHEMBL30469275 | 0.79 | ALDH1A1 (0.78) | ALDH1A1LMNATSHRGAAMGAM | |
| SCHEMBL2026676 | 0.79 | ALDH1A1 (0.78) | ALDH1A1LMNATSHRGAAMGAM | |
| SCHEMBL11656665 | 0.78 | SCN2A (0.47) | LMNATSHRMAPTABCG2MEN1 | |
| SCHEMBL9639665 | 0.78 | VCAM1 (0.42) | ALDH1A1LMNATSHRMAPTCES2 | |
| SCHEMBL5395355 | 0.78 | MAOA (0.50) | ALDH1A1LMNAMAPTKDM4EMAOA | |
| Water SCHEMBL29134001 | 0.77 | ALDH1A1 (0.75) | ALDH1A1LMNATSHRGAAMGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492358-B2 | FOR TREATMENT OF SEXUAL DISORDERS, MALE ERECTILE DYSFUNCTION | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2002-12-10 | — | — | US | claimed |