SCHEMBL7679562

SCHEMBL7679562

O=C(O)C1CCCN(CCCN2CCC(=C3c4ccccc4CSc4ccccc43)CC2)C1

nearest known ligand 0.51

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SLC6A1 P30531 2/20 0.48
FNTA P49354 1/20 0.48
FNTB P49356 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7682407 0.99 SLC6A1 (0.47) SLC6A1FNTAFNTB
SCHEMBL7672625 0.96 FNTA (0.49) SLC6A1FNTAFNTB
Hydrochloric Acid SCHEMBL7679542 0.95 FNTA (0.48) SLC6A1FNTAFNTB
SCHEMBL7678661 0.88 ALDH1A1 (0.49) FNTAFNTB
SCHEMBL7681290 0.84 ALDH1A1 (0.51) FNTAFNTB
SCHEMBL7676763 0.83 FNTA (0.55) FNTAFNTB
Hydrochloric Acid SCHEMBL9844228 0.82 FNTA (0.54) FNTAFNTB
Acetic Acid SCHEMBL7681832 0.81 FNTA (0.52) FNTAFNTB
SCHEMBL9844279 0.80 FNTA (0.54) FNTAFNTB
SCHEMBL11600654 0.80 FNTA (0.54) FNTAFNTB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020151539-A1 Novel heterocyclic compounds JORGENSEN TINE KROGH (DK) 2002-10-17 US claimed
EP-0991633-A1 NOVEL HETEROCYCLIC COMPOUNDS NOVO NORDISK A/S (DK) 2000-04-12 EP claimed
WO-1999000376-A1 NOVEL HETEROCYCLIC COMPOUNDS NOVO NORDISK A/S (DK) 1999-01-07 WO claimed
US-20020151539-A1 Novel heterocyclic compounds JORGENSEN TINE KROGH (DK) 2002-10-17 US disclosed
US-6391890-B1 ANALGESICS, ANTIINFLAMMATORY AGENTS, NON-INSULIN DEPENDENT DIABETES NOVO NORDISK A/S (DK) 2002-05-21 US disclosed
US-6054458-A Heterocyclic compounds NOVONORDISKALS (DK) 2000-04-25 US disclosed
EP-0991633-A1 NOVEL HETEROCYCLIC COMPOUNDS NOVO NORDISK A/S (DK) 2000-04-12 EP disclosed
WO-1999000376-A1 NOVEL HETEROCYCLIC COMPOUNDS NOVO NORDISK A/S (DK) 1999-01-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020151539-A1 Novel heterocyclic compounds IAPP, GPR119, NPY1R SLC6A1 4566/4885FNTA 3191/4885FNTB 2306/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.