Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.62 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.58 |
| ▸ | MAOB | P27338 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | GPR183 | P32249 | 2/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29738483 | 0.94 | ALOX5 (0.66) | GAANPC1RAB9AL3MBTL1ALOX5 | |
| SCHEMBL6786005 | 0.85 | ALDH1A1 (0.80) | NPC1RAB9AALOX5MAOBALDH1A1 | |
| SCHEMBL6785637 | 0.84 | MEN1 (0.79) | NPC1RAB9AL3MBTL1ALOX5MAOB | |
| SCHEMBL3122595 | 0.83 | NPC1 (0.72) | GAANPC1RAB9AL3MBTL1ALDH1A1 | |
| SCHEMBL3122606 | 0.83 | NPC1 (0.72) | GAANPC1RAB9AL3MBTL1ALDH1A1 | |
| SCHEMBL5573937 | 0.82 | CCR2 (0.58) | GAANPC1RAB9AL3MBTL1MAPT | |
| SCHEMBL5573940 | 0.82 | CCR2 (0.58) | GAANPC1RAB9AL3MBTL1MAPT | |
| SCHEMBL6785345 | 0.81 | ALDH1A1 (0.72) | GAANPC1RAB9AALOX5MAOB | |
| SCHEMBL6792237 | 0.81 | GPR183 (0.64) | NPC1RAB9AALOX5MAOBALDH1A1 | |
| SCHEMBL6787409 | 0.81 | ALDH1A1 (0.57) | NPC1RAB9AALOX5MAOBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6340682-B1 | FOR THERAPY OF ALLERGIC IMMUNOLOGICAL DISEASE IS SELECTED FROM ASTHMA, ALLERGIC RHINITIS, INFLAMMATORY LARGE BOWEL DISEASE OR CONTACT DERMATITIS | KOWA CO., LTD. (JP) | 2002-01-22 | — | — | US | disclosed |
| EP-0926138-A1 | DIAMIDE COMPOUNDS AND DRUGS CONTAINING THE SAME | KOWA CO. LTD. (JP) | 1999-06-30 | — | — | EP | disclosed |