Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CCNC | P24863 | 2/20 | 0.35 |
| ▸ | CDK8 | P49336 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | AVPR2 | P30518 | 3/20 | 0.35 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.35 |
| ▸ | KIT | P10721 | 1/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7679737 | 1.00 | POLB (0.40) | POLBKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL14590035 | 0.80 | TGM2 (0.44) | ALDH1A1MAPTNPSR1NPC1KDM4E | |
| SCHEMBL3557118 | 0.79 | AVPR2 (0.35) | KMT2AMEN1ALDH1A1MAPTNPSR1 | |
| SCHEMBL3557117 | 0.79 | AVPR2 (0.35) | KMT2AMEN1ALDH1A1MAPTNPSR1 | |
| SCHEMBL14590031 | 0.77 | ALDH1A1 (0.34) | POLBKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL7680383 | 0.72 | CYP2C19 (0.45) | ALDH1A1KDM4E | |
| SCHEMBL7682770 | 0.70 | KCNN4 (0.42) | POLBKMT2AMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL7682776 | 0.70 | KCNN4 (0.42) | POLBKMT2AMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL5377463 | 0.70 | SLC6A2 (0.35) | ALDH1A1KDM4EAVPR2AVPR1A | |
| SCHEMBL5377456 | 0.70 | SLC6A2 (0.35) | ALDH1A1KDM4EAVPR2AVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6340678-B1 | FOR THERAPY OF THREATENED PREMATURE BIRTH OR ABORTION, DYSMENORRHEA, CONTRACTION OF UTERINE SMOOTH MUSCLE, RELEASE OF MILK, ENDOMETRIOSIS, NEED FOR FEEDING CONTROL, DISTURBANCE OF MEMORY, NATRIURESIS, NEED FOR CARBOHYDRATE METABOLISM | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 2002-01-22 | — | — | US | disclosed |
| EP-0987264-A1 | 4,4-DIFLUORO-2,3,4,5-TETRAHYDRO-1H-1-BENZAZEPINE DERIVATIVES AND DRUG COMPOSITIONS CONTAINING THEM | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 2000-03-22 | — | — | EP | disclosed |