SCHEMBL768038

SCHEMBL768038

CNC(=O)C(C)Br

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1771013 1.00
SCHEMBL146291 0.78
SCHEMBL16106184 0.78
SCHEMBL3315856 0.78
SCHEMBL3313675 0.78
SCHEMBL23124402 0.78 ALDH1A1 (0.32)
SCHEMBL18619440 0.77
SCHEMBL6934715 0.75
SCHEMBL103435 0.73
SCHEMBL7524063 0.73 FFAR2 (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12612414-B2 Nitrile SUMO inhibitors and uses thereof CIT THERAPEUTICS, INC. (US) 2026-04-28 US disclosed
US-20240360148-A1 NITRILE SUMO INHIBITORS AND USES THEREOF CIT THERAPEUTICS LLC 2024-10-31 US disclosed
EP-4373825-A1 NITRILE SUMO INHIBITORS AND USES THEREOF Suvalent Therapeutics, Inc. (US) 2024-05-29 EP disclosed
EP-3659591-B1 MULTIFUNCTIONAL ZWITTERIONIC POLYMER CONJUGATES KODIAK SCIENCES INC (US) 2023-10-25 EP disclosed
US-11746178-B2 Polymer production method and radical polymerization initiating group-containing compound DAINICHISEIKA COLOR & CHEMICALS MFG. CO., LTD. (JP) 2023-09-05 US disclosed
US-11746178-B2 Polymer production method and radical polymerization initiating group-containing compound DAINICHISEIKA COLOR & CHEMICALS MFG. CO., LTD. (JP) 2023-09-05 US disclosed
WO-2023004376-A1 NITRILE SUMO INHIBITORS AND USES THEREOF Suvalent Therapeutics, Inc. (US) 2023-01-26 WO disclosed
EP-3604354-B1 PRODUCTION METHOD FOR POLYMER DAINICHISEIKA COLOR CHEM (JP) 2022-02-02 EP disclosed
EP-3549963-B1 HIGH MOLECULAR WEIGHT ZWITTERION-CONTAINING POLYMERS KODIAK SCIENCES INC (US) 2022-01-12 EP disclosed
US-10947213-B1 TLR7/8 antagonists and uses thereof MERCK PATENT GMBH (DE) 2021-03-16 US disclosed
WO-2011143430-A1 INDAZOLE INHIBITORS OF KINASE ABBOTT LABORATORIES (US) 2011-11-17 WO disclosed
WO-2011130694-A2 HIGH MOLECULAR WEIGHT ZWITTERION-CONTAINING POLYMERS OLIGASIS (US) 2011-10-20 WO disclosed
WO-2011075185-A1 TARGETED DRUG PHOSPHORYLCHOLINE POLYMER CONJUGATES OLIGASIS (US) 2011-06-23 WO disclosed
US-20110112063-A1 PYRIMIDINE DERIVATIVES AS KINASE INHIBITORS IRM LLC (BM) 2011-05-12 US disclosed
EP-2318392-A2 PYRIMIDINE DERIVATIVES AS KINASE INHIBITORS IRM LLC (BM) 2011-05-11 EP disclosed
WO-2010015588-A1 BENZYL-SUBSTITUTED TETRACYCLIC HETEROCYCLIC COMPOUNDS NYCOMED GMBH (DE) 2010-02-11 WO disclosed
WO-2010002655-A2 COMPOUNDS AND COMPOSITIONS AS KINASE INHIBITORS IRM LLC (BM) 2010-01-07 WO disclosed
US-20090130187-A1 Covalent Conjugates of Cotton and Substitutes (Viscose, Modal Cotton) with Bioactive Substances Having Antiseptic, Sanitizing, Acaricidal and Insect Repellent Activity, and a Method for Obtaining Them FRANZONI FILATI S.P.A. (IT) 2009-05-21 US disclosed
US-20090098074-A1 Keratin-Binding Effector Molecules Containing Reactive Dyes BASF SE (DE) 2009-04-16 US disclosed
US-5108489-A HERBICIDAL DISUBSTITUTED NAPHTHALENES BAYER AKTIENGESELLSCHAFT (DE) 1992-04-28 US disclosed