Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.44 |
| ▸ | ANPEP | P15144 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA3 | P07451 | 1/20 | 0.43 |
| ▸ | TYR | P14679 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1753887 | 0.91 | TSHR (0.55) | TSHRTP53ALDH1A1SMN1; SMN2SRD5A2 | |
| SCHEMBL1753679 | 0.86 | TSHR (0.48) | TSHRTP53ALDH1A1SMN1; SMN2SRD5A2 | |
| SCHEMBL2427033 | 0.81 | SRC (0.48) | ALDH1A1SMN1; SMN2SRCSRD5A2POLB | |
| SCHEMBL3678814 | 0.80 | SRC (0.73) | ALDH1A1SRCKMT2AHPGDTDP1 | |
| SCHEMBL7303581 | 0.80 | SRC (0.73) | ALDH1A1SRCKMT2AHPGDTDP1 | |
| SCHEMBL22265095 | 0.79 | BRD4 (0.57) | TSHRSRCKMT2AALOX15POLB | |
| SCHEMBL7821350 | 0.79 | SRC (0.46) | ALDH1A1SMN1; SMN2SRCKMT2APOLB | |
| SCHEMBL8672582 | 0.79 | SRC (0.46) | TSHRALDH1A1SMN1; SMN2SRCPOLB | |
| SCHEMBL6187748 | 0.78 | PTGS2 (0.60) | SMN1; SMN2SRC | |
| SCHEMBL10936588 | 0.77 | TSHR (0.52) | TSHRTP53ALDH1A1SMN1; SMN2SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6358971-B1 | FOR INHIBITING THE GROWTH OF A PICORNAVIRUS | ELI LILLY AND COMPANY | 2002-03-19 | — | — | US | disclosed |