SCHEMBL7680680

SCHEMBL7680680

CCN(CCCCCCN(CC)CC(O)COC1CC(C)(C)N(O)C(C)(C)C1)CC(O)COC1CC(C)(C)N(O)C(C)(C)C1

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.32
ABCB11 O95342 1/20 0.31
KCNH2 Q12809 1/20 0.31
KDM4E B2RXH2 1/20 0.30
MAPK1 P28482 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7515898 0.91 LMNA (0.43) LMNAL3MBTL1
SCHEMBL7514116 0.84 GGPS1 (0.31)
SCHEMBL5400020 0.84 KDM4E (0.33) LMNAKDM4EMAPK1TDP1
SCHEMBL7518617 0.83 ALDH1A1 (0.43) LMNAKDM4E
SCHEMBL7512516 0.79 HIF1A (0.33) LMNAL3MBTL1
SCHEMBL18417984 0.77 KMT2A (0.33) MAPK1
SCHEMBL2025232 0.74 GAA (0.33) L3MBTL1
SCHEMBL5406094 0.73 KDM4E (0.33) KDM4EMAPK1TDP1
SCHEMBL987956 0.73 MEN1 (0.33) L3MBTL1
SCHEMBL5405789 0.73 KDM4E (0.32) KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6500303-B1 DERIVATIVES OF 1-OXYL-2,2,6,6-TETRAMETHYL-PIPERIDIN-4-OL; PROTECTION FROM ULTRAVIOLET, FLUORESCENT AND SUN LIGHT EXPOSURE CIBA SPECIALTY CHEMICALS CORPORATION 2002-12-31 US claimed