Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5400020 | 0.89 | KDM4E (0.33) | KDM4EMAPK1TDP1MEN1KMT2A | |
| SCHEMBL5405785 | 0.73 | TOP2A (0.31) | KDM4EMEN1KMT2A | |
| SCHEMBL7680680 | 0.73 | LMNA (0.36) | KDM4EMAPK1TDP1 | |
| SCHEMBL8437640 | 0.73 | KDM4E (0.42) | KDM4EMAPK1TDP1MEN1KMT2A | |
| SCHEMBL7515898 | 0.71 | LMNA (0.43) | MEN1KMT2A | |
| SCHEMBL7518617 | 0.69 | ALDH1A1 (0.43) | KDM4E | |
| SCHEMBL2437027 | 0.68 | EPHX2 (0.33) | — | |
| SCHEMBL7512516 | 0.67 | HIF1A (0.33) | MEN1KMT2A | |
| SCHEMBL8437206 | 0.67 | DNM1 (0.38) | KDM4EMAPK1TDP1MEN1KMT2A | |
| SCHEMBL2163885 | 0.67 | MEN1 (0.33) | KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7312332-B2 | Such as 1-butyl-3-hydroxy-1-[2-hydroxy-3-(1-oxyl-2,2,6,6-tetramethyl-piperidin-4-yloxy)-propyl]-azetidinium chloride; yellowing and discoloration prevention; ultraviolet, fluorescent and solar light stability; expanding use of high yield pulps to higher grade products | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2007-12-25 | — | — | US | disclosed |
| US-6989449-B1 | Chlorohydrin and cationic compounds having high affinity for pulp or paper | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2006-01-24 | — | — | US | disclosed |
| US-20050092452-A1 | Chlorohydrin and cationic compounds having high affinity for pulp or paper | CUNKLE GLEN T (US) | 2005-05-05 | — | — | US | disclosed |
| EP-1212486-B1 | CHLOROHYDRIN AND CATIONIC COMPOUNDS HAVING HIGH AFFINITY FOR PULP OR PAPER | CIBA SC HOLDING AG (CH) | 2005-04-06 | — | — | EP | disclosed |
| EP-1212486-A1 | CHLOROHYDRIN AND CATIONIC COMPOUNDS HAVING HIGH AFFINITY FOR PULP OR PAPER | Ciba SC Holding AG (CH) | 2002-06-12 | — | — | EP | disclosed |
| WO-2001020078-A1 | CHLOROHYDRIN AND CATIONIC COMPOUNDS HAVING HIGH AFFINITY FOR PULP OR PAPER | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2001-03-22 | — | — | WO | disclosed |