SCHEMBL7680840

SCHEMBL7680840

O=C(O)C1=C(Cl)CC(=Cc2ccccc2)C(Cl)=C1Cl

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.41
MAOB P27338 6/20 0.39
MAOA P21397 3/20 0.39
F3 P13726 1/20 0.39
MIF P14174 2/20 0.38
ALDH1A1 P00352 3/20 0.38
HTT P42858 2/20 0.38
ACHE P22303 1/20 0.37
MGAM O43451 2/20 0.36
GAA P10253 2/20 0.36
SI P14410 2/20 0.36
MGAM2 Q2M2H8 2/20 0.36
HPGD P15428 2/20 0.35
LMNA P02545 1/20 0.35
AKT1 P31749 1/20 0.35
AKT2 P31751 1/20 0.35
AKT3 Q9Y243 1/20 0.35
MAPT P10636 2/20 0.35
MEN1 O00255 1/20 0.35
MAPK1 P28482 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9149752 0.65 CYP1A2 (0.41) CYP1A2MAOBMAOAF3MIF
SCHEMBL5345283 0.61 CYP1A2 (0.41) CYP1A2MAOBMAOAF3MIF
SCHEMBL7966253 0.60 MAOB (0.57) CYP1A2MAOBMAOAF3MIF
SCHEMBL7966250 0.60 MAOB (0.57) CYP1A2MAOBMAOAF3MIF
SCHEMBL23633272 0.59 CYP1A2 (1.00) CYP1A2MAOBF3MIFALDH1A1
SCHEMBL12948629 0.59 CYP1A2 (1.00) CYP1A2MAOBF3MIFALDH1A1
SCHEMBL978681 0.59 CYP1A2 (1.00) CYP1A2MAOBF3MIFALDH1A1
SCHEMBL3128602 0.59 CYP1A2 (1.00) CYP1A2MAOBF3MIFALDH1A1
SCHEMBL15782144 0.59 CYP1A2 (0.55) CYP1A2MAOBMAOAF3MIF
SCHEMBL17175849 0.58 ACHE (0.71) CYP1A2F3ALDH1A1ACHEMGAM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6432878-B1 FOR PESTICIDES, HERBICIDES; WATER SOLUBLE ADJUVANTS COGNIS CORPORATION 2002-08-13 US disclosed