SCHEMBL5345283

SCHEMBL5345283

NC1=CC=C(C(=O)O)C(=Cc2ccccc2)C1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.41
F3 P13726 1/20 0.39
MAOB P27338 4/20 0.38
MAOA P21397 3/20 0.38
HPGD P15428 2/20 0.38
MIF P14174 1/20 0.38
LMNA P02545 1/20 0.38
AKT1 P31749 1/20 0.38
AKT2 P31751 1/20 0.38
AKT3 Q9Y243 1/20 0.38
ALDH1A1 P00352 3/20 0.38
HTT P42858 1/20 0.38
ACHE P22303 1/20 0.37
HDAC1 Q13547 6/20 0.36
MGAM O43451 1/20 0.36
GAA P10253 1/20 0.36
SI P14410 1/20 0.36
MGAM2 Q2M2H8 1/20 0.36
MEN1 O00255 2/20 0.35
MAPT P10636 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11179058 0.86 AKR1C3 (0.40) CYP1A2MAOBMAOAHPGDALDH1A1
SCHEMBL5350966 0.83 MAOA (0.41) MAOBMAOAHPGDMIFLMNA
SCHEMBL11430522 0.82 MIF (0.43) MIFLMNAHDAC1MAPT
SCHEMBL11795095 0.71 ALDH1A1 (0.39) CYP1A2F3MAOBMAOAHPGD
SCHEMBL11779755 0.63 MAOB (0.44) CYP1A2F3MAOBMAOAMIF
SCHEMBL8401481 0.62 CYP1A2 (0.33) CYP1A2F3MAOBMAOAMIF
SCHEMBL7680840 0.61 CYP1A2 (0.41) CYP1A2F3MAOBMAOAHPGD
SCHEMBL11034824 0.61 CYP1B1 (0.35) CYP1A2F3MAOBMAOAHPGD
SCHEMBL28937832 0.60 CYP1A2 (0.40) CYP1A2F3MAOBMAOAHPGD
SCHEMBL7966253 0.60 MAOB (0.57) CYP1A2F3MAOBMAOAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100388095-C Display apparatus SHARP KK (JP) 2008-05-14 CN disclosed
US-7186448-B2 Composition and method for temporarily fixing solid JSR CORPORATION (JP) 2007-03-06 US disclosed
US-20060275939-A1 Composition and method for temporarily fixing solids JSR CORPORATION (JP) 2006-12-07 US disclosed
EP-1522567-A1 COMPOSITION AND METHOD FOR TEMPORARILY FIXING SOLID JSR Corporation (JP) 2005-04-13 EP disclosed
CN-1584722-A Display apparatus SHARP KK (JP) 2005-02-23 CN disclosed
US-20040185187-A1 Composition and method for temporarily fixing solid JSR CORPORATION (JP) 2004-09-23 US disclosed
US-3968159-A Process for preparing azomethines MONSANTO COMPANY (US) 1976-07-06 US disclosed