Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP1LC3B | Q9GZQ8 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7681124 | 0.85 | MAP1LC3B (0.42) | MAP1LC3BHPGDHTR2CMAPTMEN1 | |
| SCHEMBL7683976 | 0.82 | MAP1LC3B (0.41) | MAP1LC3BHPGDMAPTMEN1KMT2A | |
| SCHEMBL7689638 | 0.82 | TP53 (0.48) | MAP1LC3BHPGDMAPTPKMALDH1A1 | |
| SCHEMBL7683611 | 0.82 | MAP1LC3B (0.49) | MAP1LC3BHPGDPKMALDH1A1LMNA | |
| SCHEMBL7680946 | 0.79 | HTR2C (0.40) | HTR2CMAPTLMNA | |
| SCHEMBL7685368 | 0.78 | LMNA (0.58) | MAP1LC3BHPGDMAPTMEN1KMT2A | |
| SCHEMBL7683942 | 0.77 | MAP1LC3B (0.44) | MAP1LC3BHTR2CPKMALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL7685354 | 0.75 | HTR2C (0.34) | MAP1LC3BHTR2CPKM | |
| SCHEMBL7689326 | 0.75 | GRM7 (0.42) | HPGDKMT2AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL7687099 | 0.74 | TP53 (0.35) | HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6350749-B1 | SODIUM CHANNEL MODULATORS, ANTIARRHYTHMIA AND HYPOTENSIVE AGENTS; CARDIOVASCULAR DISORDERS, ANGINA PECTORIS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-02-26 | — | — | US | disclosed |
| EP-1057812-A1 | AMINOGUANIDINE HYDRAZONE DERIVATIVES, PROCESS FOR PRODUCING THE SAME AND DRUGS THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2000-12-06 | — | — | EP | disclosed |