Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.40 |
| ▸ | RBP4 | P02753 | 8/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7690067 | 0.85 | MAP1LC3B (0.38) | HTR2CRBP4LMNAMAPT | |
| SCHEMBL7681124 | 0.84 | MAP1LC3B (0.42) | HTR2CLMNAMAPT | |
| SCHEMBL7683976 | 0.83 | MAP1LC3B (0.41) | LMNAMAPT | |
| SCHEMBL7683611 | 0.81 | MAP1LC3B (0.49) | LMNA | |
| SCHEMBL7689638 | 0.81 | TP53 (0.48) | LMNATP53MAPT | |
| SCHEMBL7680888 | 0.79 | MAP1LC3B (0.51) | HTR2CLMNAMAPT | |
| SCHEMBL7689655 | 0.78 | MAP1LC3B (0.43) | HTR2CRBP4LMNA | |
| SCHEMBL7685368 | 0.77 | LMNA (0.58) | LMNATP53MAPT | |
| SCHEMBL7683942 | 0.76 | MAP1LC3B (0.44) | HTR2CLMNAHTR2BTP53 | |
| Hydrochloric Acid SCHEMBL7683308 | 0.75 | HTR2C (0.34) | HTR2CRBP4HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6350749-B1 | SODIUM CHANNEL MODULATORS, ANTIARRHYTHMIA AND HYPOTENSIVE AGENTS; CARDIOVASCULAR DISORDERS, ANGINA PECTORIS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-02-26 | — | — | US | disclosed |
| EP-1057812-A1 | AMINOGUANIDINE HYDRAZONE DERIVATIVES, PROCESS FOR PRODUCING THE SAME AND DRUGS THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2000-12-06 | — | — | EP | disclosed |