Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MC4R | P32245 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7679625 | 0.76 | HRH3 (0.39) | KDM4EMC4RLMNA | |
| SCHEMBL7678922 | 0.76 | HRH3 (0.39) | KDM4EMC4RLMNA | |
| SCHEMBL7680859 | 0.74 | HTR2C (0.38) | — | |
| SCHEMBL7679970 | 0.74 | MC4R (0.42) | KDM4EMC4RLMNA | |
| SCHEMBL27501203 | 0.73 | CHIA (0.35) | KDM4ELMNA | |
| SCHEMBL27471040 | 0.72 | PDE10A (0.39) | — | |
| SCHEMBL7681799 | 0.70 | JAK3 (0.37) | KDM4ELMNA | |
| SCHEMBL27471926 | 0.68 | KHK (0.41) | — | |
| SCHEMBL25192407 | 0.68 | CYP2A6 (0.35) | KDM4E | |
| SCHEMBL7682554 | 0.65 | HRH4 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6455520-B1 | TUMOR NECROSIS FACTOR AND INTERLEUKIN INHIBITORS; ANTIINFLAMMATORY AGENTS, ANTIALLERGENS; BONE DISORDERS | ASTRA ZENECA AB (SE) | 2002-09-24 | — | — | US | disclosed |