Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 13/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27501203 | 0.88 | CHIA (0.35) | KCNH2PIK3CAMTORACHEHRH3 | |
| SCHEMBL27471926 | 0.88 | KHK (0.41) | PDE10APIK3CAMTOR | |
| SCHEMBL7680859 | 0.84 | HTR2C (0.38) | — | |
| SCHEMBL7678922 | 0.83 | HRH3 (0.39) | HRH3 | |
| SCHEMBL7679625 | 0.83 | HRH3 (0.39) | HRH3 | |
| SCHEMBL7679628 | 0.81 | MC4R (0.37) | — | |
| SCHEMBL7681799 | 0.79 | JAK3 (0.37) | PDE10A | |
| SCHEMBL7672759 | 0.74 | KDM4E (0.43) | PIK3CA | |
| SCHEMBL7679970 | 0.73 | MC4R (0.42) | HRH3 | |
| SCHEMBL7681200 | 0.72 | KDM4E (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1146542-C | Benzamide derivatives and their use as cytokine inhibitors | — | 2004-04-21 | — | — | CN | disclosed |
| CN-1319092-A | Benzamide derivatives and their use as cytokine inhibitors | ASTRAZENECA AB (SE) | 2001-10-24 | — | — | CN | disclosed |