Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PTGES | O14684 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7682078 | 0.91 | ALDH1A1 (0.42) | ALDH1A1KDM4ESORT1HPGDNPC1 | |
| SCHEMBL7682836 | 0.85 | KDM4E (0.39) | ALDH1A1KDM4EHPGDNPC1ALOX12 | |
| SCHEMBL7682639 | 0.85 | ALDH1A1 (0.38) | GRM5GRM1ALDH1A1KDM4ESORT1 | |
| SCHEMBL7679306 | 0.84 | ALDH1A1 (0.40) | ALDH1A1KDM4ESORT1HPGDNPC1 | |
| SCHEMBL7685899 | 0.84 | ALDH1A1 (0.37) | GRM5GRM1ALDH1A1KDM4ESORT1 | |
| SCHEMBL7686045 | 0.83 | HPGD (0.44) | ALDH1A1KDM4EHPGDNPC1ALOX12 | |
| SCHEMBL7684280 | 0.80 | CNR1 (0.43) | NPC1 | |
| SCHEMBL7684146 | 0.77 | MAPT (0.35) | GRM5GRM1ALDH1A1KDM4EHPGD | |
| SCHEMBL7684669 | 0.76 | MAPT (0.34) | GRM5GRM1ALDH1A1KDM4EHPGD | |
| SCHEMBL7684085 | 0.75 | PDE4D (0.40) | ALDH1A1SORT1HPGDSMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6472349-B1 | Pyridine-2,3-dicarboxylic acid diamides | BASF AKTIENGESELLSCHAFT (DE) | 2002-10-29 | — | — | US | claimed |