Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.34 |
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7684669 | 0.91 | MAPT (0.34) | MAPTTP53GRM5GRM1STAT3 | |
| SCHEMBL7685879 | 0.91 | MAPT (0.34) | MAPTGRM5KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL7682639 | 0.89 | ALDH1A1 (0.38) | MAPTTP53GRM5GRM1STAT3 | |
| SCHEMBL7677560 | 0.86 | GRM5 (0.35) | MAPTTP53GRM5GRM1KMT2A | |
| SCHEMBL7685639 | 0.85 | ALDH1A1 (0.36) | MAPTTP53KMT2AMEN1ALDH1A1 | |
| SCHEMBL7679294 | 0.84 | ALDH1A1 (0.34) | MAPTKMT2AMEN1ALDH1A1HTT | |
| SCHEMBL7679448 | 0.84 | SMN1; SMN2 (0.33) | MAPTGRM5KMT2AMEN1ALDH1A1 | |
| SCHEMBL7682616 | 0.83 | ALDH1A1 (0.39) | TP53ALDH1A1HTTL3MBTL1TSHR | |
| SCHEMBL7685899 | 0.80 | ALDH1A1 (0.37) | MAPTTP53GRM5GRM1STAT3 | |
| SCHEMBL7686030 | 0.80 | PTGS2 (0.35) | MAPTKMT2AMEN1ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6472349-B1 | Pyridine-2,3-dicarboxylic acid diamides | BASF AKTIENGESELLSCHAFT (DE) | 2002-10-29 | — | — | US | claimed |