Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 5/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.40 |
| ▸ | PDE4A | P27815 | 4/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.40 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7682639 | 0.91 | ALDH1A1 (0.38) | PDE4DPDE4BPDE4APDE4CSORT1 | |
| SCHEMBL7685456 | 0.88 | TSHR (0.39) | PDE4DPDE4BPDE4APDE4CSORT1 | |
| SCHEMBL7685879 | 0.87 | MAPT (0.34) | PDE4DPDE4BPDE4APDE4CSORT1 | |
| SCHEMBL7683047 | 0.85 | PDE4A (0.38) | PDE4DPDE4BPDE4APDE4CSORT1 | |
| SCHEMBL7683343 | 0.83 | PDE4B (0.39) | PDE4DPDE4BPDE4APDE4CSORT1 | |
| SCHEMBL7682078 | 0.83 | ALDH1A1 (0.42) | SORT1RXFP1LMNAMAPTHPGD | |
| SCHEMBL7685558 | 0.83 | PTGS2 (0.42) | PDE4DPDE4BPDE4APDE4CSORT1 | |
| SCHEMBL7677586 | 0.83 | HTT (0.41) | PDE4DPDE4BPDE4APDE4CS1PR4 | |
| SCHEMBL7685899 | 0.82 | ALDH1A1 (0.37) | PDE4DPDE4BPDE4APDE4CSORT1 | |
| SCHEMBL678914 | 0.82 | P2RX7 (0.38) | PDE4DPDE4BPDE4APDE4CSORT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6472349-B1 | Pyridine-2,3-dicarboxylic acid diamides | BASF AKTIENGESELLSCHAFT (DE) | 2002-10-29 | — | — | US | claimed |