Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | MDM4 | O15151 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6316890 | 0.82 | PTPN1 (0.42) | EPHX2ALDH1A1KMT2AMEN1USP2 | |
| SCHEMBL7127946 | 0.77 | ALDH1A1 (0.43) | ALDH1A1KMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL6402811 | 0.74 | CXCR2 (0.39) | EPHX2ALDH1A1PTPN1 | |
| SCHEMBL6316896 | 0.68 | RAB7A (0.37) | EPHX2ALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL23413466 | 0.64 | FABP5 (0.47) | EPHX2ALDH1A1KMT2AMEN1HTT | |
| SCHEMBL30000091 | 0.64 | FABP5 (0.47) | EPHX2ALDH1A1KMT2AMEN1HTT | |
| SCHEMBL30300681 | 0.64 | EPHX2 (0.45) | EPHX2ALDH1A1KMT2AMEN1HTT | |
| SCHEMBL3051843 | 0.64 | EPHX2 (0.55) | EPHX2KMT2A | |
| SCHEMBL6207147 | 0.64 | PTPN1 (0.51) | CYP1A2CYP2C9CYP2C19PTPN1 | |
| SCHEMBL8366872 | 0.63 | EPHX2 (0.75) | EPHX2ALDH1A1KMT2AMEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410586-B1 | ANTICOAGULANTS; INSULIN RESISTANCE; ANTIALLERGENS | NOVO NORDISK A/S (DK) | 2002-06-25 | — | — | US | disclosed |