Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 2/20 | 0.56 |
| ▸ | BLM | P54132 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | RECQL | P46063 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | APEX1 | P27695 | 2/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.50 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31419997 | 1.00 | PNMT (0.56) | PNMTBLMMAPTRECQLTDP1 | |
| SCHEMBL3489554 | 1.00 | PNMT (0.56) | PNMTBLMMAPTRECQLTDP1 | |
| SCHEMBL768007 | 1.00 | PNMT (0.56) | PNMTBLMMAPTRECQLTDP1 | |
| Hydrochloric Acid SCHEMBL4465387 | 0.98 | PNMT (0.54) | PNMTBLMMAPTRECQLTDP1 | |
| Hydrochloric Acid SCHEMBL2327859 | 0.98 | PNMT (0.54) | PNMTBLMMAPTRECQLTDP1 | |
| Hydrochloric Acid SCHEMBL4802312 | 0.98 | PNMT (0.54) | PNMTBLMMAPTRECQLTDP1 | |
| Hydrochloric Acid SCHEMBL31332749 | 0.98 | PNMT (0.54) | PNMTBLMMAPTRECQLTDP1 | |
| Bicarbonate SCHEMBL9515153 | 0.93 | KDM4E (0.51) | PNMTBLMMAPTRECQLTDP1 | |
| SCHEMBL10318241 | 0.85 | ADRB2 (0.44) | PNMTTAAR1ADRB2ADRB1ADRB3 | |
| SCHEMBL1154749 | 0.83 | ADRB3 (0.49) | ADRB2ADRB1ADRB3LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 223 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5914339-A | ANTI-DIABETIC AND/OR ANTIHYPERGLYCEMIA AND/OR ANTI-OBESITY AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-06-22 | — | — | US | claimed |
| US-5236951-A | Administering a phenylethanolamine derivative | SANOFI (FR) | 1993-08-17 | — | — | US | claimed |
| EP-0403360-A2 | Use of phenylethanolamines for the preparation of a medicament for treating ophthalmologic disorders | SANOFI (FR) | 1990-12-19 | — | — | EP | claimed |
| JP-7112958-A | — | — | None | — | — | JP | disclosed |
| JP-10007628-A | — | — | None | — | — | JP | disclosed |
| EP-4743460-A1 | CRYSTALLINE FORM OF (S)-1-(1- (3-CHLOROPHENYL)-2-(DIMETHYLAMINO) ETHYL)-4- (5 -MORPHOLINO -1H-PYRROLO[2,3-B]PYRIDIN -3-YL)PYRIDIN-2 (1H)-ONE, ITS PREPARATION AND ITS USE AS ERK KINASE INHIBITOR | AGV Discovery (FR) | 2026-05-20 | — | — | EP | disclosed |
| EP-4743461-A1 | (S)-1-(1- (3-CHLOROPHENYL)-2-(DIMETHYLAMINO) ETHYL)-4-(5 -MORPHOLINO-1H- PYRROLO[2,3-B]PYRIDIN-3-YL) PYRIDIN-2(1H)-ONE,THEIR PREPARATION AND THEIR USE AS ERK KINASE INHIBITORS | AGV Discovery (FR) | 2026-05-20 | — | — | EP | disclosed |
| EP-4709708-A1 | NOVEL CARBOXAMIDE DERIVATIVES | ANGELINI PHARMA S.P.A. (IT) | 2026-03-18 | — | — | EP | disclosed |
| US-20260042758-A1 | AZAINDOLE DERIVATIVES AND THEIR USE AS ERK KINASE INHIBITORS | AGV DISCOVERY (FR) | 2026-02-12 | — | — | US | disclosed |
| WO-2025012386-A1 | CRYSTALLINE FORM OF (S)-1-(1-(3-CHLOROPHENYL)-2- (DIMETHYLAMINO)ETHYL)-4-(5-MORPHOLINO-1H-PYRROLO[2,3- B]PYRIDIN-3-YL)PYRIDIN-2(1H)-ONE, ITS PREPARATION AND ITS USE AS ERK KINASE INHIBITOR | AGV DISCOVERY (FR) | 2025-01-16 | — | — | WO | disclosed |
| WO-2025012389-A1 | SALTS OF (S)-1-(1-(3-CHLOROPHENYL)-2-(DIMETHYLAMINO)ETHYL)-4-(5- MORPHOLINO-1H-PYRROLO[2,3-B]PYRIDIN-3-YL)PYRIDIN-2(1H)-ONE, THEIR PREPARATION AND THEIR USE AS ERK KINASE INHIBITORS | AGV DISCOVERY (FR) | 2025-01-16 | — | — | WO | disclosed |
| US-4309443-A | ANTI-OBESITY, HYPOGLYCEMIC | BEECHAM GROUP LIMITED (GB) | 1982-01-05 | — | — | US | disclosed |
| EP-0040000-A1 | Arylethanolamine derivatives, their preparation and use in pharmaceutical compositions | BEECHAM GROUP PLC (GB) | 1981-11-18 | — | — | EP | disclosed |
| EP-0028105-A1 | Secondary amines, their preparation and use in pharmaceutical compositions | BEECHAM GROUP PLC (GB) | 1981-05-06 | — | — | EP | disclosed |
| EP-0025331-A1 | Cinnamic acid derivatives, their preparation, and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1981-03-18 | — | — | EP | disclosed |
| EP-0023385-A1 | Ethanamine derivatives, their preparation and use in pharmaceutical compositions | BEECHAM GROUP PLC (GB) | 1981-02-04 | — | — | EP | disclosed |
| EP-0021636-A1 | Secondary amines, their preparation and use in pharmaceutical compositions | BEECHAM GROUP PLC (GB) | 1981-01-07 | — | — | EP | disclosed |
| US-3983133-A | CNS ANTIDEPRESSANTS | JANSSEN PHARMACEUTICA N.V. (BE) | 1976-09-28 | — | — | US | disclosed |
| US-3963718-A | CENTRAL NERVOUS SYSTEM ANTIDEPRESSANTS | JANSSEN PHARMACEUTICA (BE) | 1976-06-15 | — | — | US | disclosed |
| US-3947456-A | ANTIDEPRESSANTS | HOFFMAN-LA ROCHE INC. (US) | 1976-03-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260042758-A1 | AZAINDOLE DERIVATIVES AND THEIR USE AS ERK KINASE INHIBITORS | BRAF, RAF1, NRAS | PNMT 3081/4885BLM 4576/4885MAPT 4808/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.