Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | PLG | P00747 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | CTSG | P08311 | 1/20 | 0.42 |
| ▸ | CMA1 | P23946 | 1/20 | 0.42 |
| ▸ | CTRC | Q99895 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7465763 | 0.69 | EP300 (0.44) | EP300F2PLGELANECTSG | |
| SCHEMBL7440132 | 0.67 | HDAC8 (0.46) | GAAPOLBHDAC8CYP1A2CYP3A4 | |
| SCHEMBL7333420 | 0.67 | HDAC8 (0.46) | GAAPOLBHDAC8CYP1A2CYP3A4 | |
| SCHEMBL9085097 | 0.66 | HDAC8 (0.45) | GAAPOLBHDAC8CYP1A2CYP3A4 | |
| SCHEMBL6936117 | 0.65 | ALDH1A1 (0.57) | MAPTPOLBHDAC2HDAC8HDAC6 | |
| SCHEMBL17070912 | 0.64 | EP300 (0.48) | EP300GFERGAAPOLBHDAC8 | |
| SCHEMBL7097780 | 0.64 | GFER (0.66) | GFERMMP1MMP3MMP9HDAC2 | |
| SCHEMBL1732657 | 0.62 | PTPN1 (0.53) | F2PLGELANECTSGCMA1 | |
| SCHEMBL7441792 | 0.62 | DDB1 (0.49) | HDAC8KMT2A | |
| SCHEMBL1226583 | 0.62 | HDAC8 (0.56) | GAAPOLBHDAC8CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6420401-B1 | SERINE PROTEASE INHIBITOR | WICHITA STATE UNIVERSITY | 2002-07-16 | — | — | US | disclosed |
| EP-1011668-A4 | 1,2,5-THIADIAZOLIDIN-3-ONE 1,1-DIOXIDE DERIVATIVES | UNIV WICHITA STATE (US) | 2001-08-16 | — | — | EP | disclosed |
| EP-1011668-A1 | 1,2,5-THIADIAZOLIDIN-3-ONE 1,1-DIOXIDE DERIVATIVES | THE WICHITA STATE UNIVERSITY (US) | 2000-06-28 | — | — | EP | disclosed |
| WO-1999009977-A9 | 1,2,5-THIADIAZOLIDIN-3-ONE 1,1-DIOXIDE DERIVATIVES | UNIV WICHITA STATE (US) | 1999-06-24 | — | — | WO | disclosed |
| WO-1999009977-A1 | 1,2,5-THIADIAZOLIDIN-3-ONE 1,1-DIOXIDE DERIVATIVES | WICHITA STATE UNIVERSITY (US) | 1999-03-04 | — | — | WO | disclosed |