Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 19/20 | 0.71 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17358769 | 0.82 | LSS (0.98) | LSSMEN1KMT2A | |
| SCHEMBL7681900 | 0.79 | LSS (1.00) | LSSMEN1KMT2A | |
| SCHEMBL7681754 | 0.77 | LSS (0.44) | LSSMEN1KMT2AKDM4E | |
| SCHEMBL23175185 | 0.73 | RAB9A (0.57) | MEN1KMT2AKDM4E | |
| SCHEMBL3440830 | 0.71 | DRD2 (0.52) | LSSMEN1KMT2AKDM4E | |
| SCHEMBL8485029 | 0.69 | LSS (0.65) | LSSMEN1KMT2A | |
| SCHEMBL6433586 | 0.69 | LMNA (0.68) | MEN1KMT2A | |
| SCHEMBL5898795 | 0.69 | LMNA (0.68) | MEN1KMT2A | |
| SCHEMBL19783672 | 0.69 | PPARA (0.61) | MEN1KMT2A | |
| SCHEMBL536375 | 0.69 | LMNA (0.68) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6441177-B1 | Tertiary amines | HOFFMANN-LA ROCHE INC. | 2002-08-27 | — | — | US | claimed |
| EP-0778264-B1 | Tertiary amines having antimycotic and cholesterol lowering activity | HOFFMANN LA ROCHE (CH) | 2001-07-11 | — | — | EP | claimed |
| US-6034275-A | FUGICIDES; ATICHOLESTEROL AGENTS | HOFFMANN-LA ROCHE INC. (US) | 2000-03-07 | — | — | US | claimed |
| CN-1158844-A | Tertiary amines | HOFFMANN LA ROCHE (CH) | 1997-09-10 | — | — | CN | claimed |
| EP-0778264-A1 | Tertiary amines having antimycotic and cholesterol lowering activity | F. HOFFMANN-LA ROCHE AG (CH) | 1997-06-11 | — | — | EP | claimed |
| US-6441177-B1 | Tertiary amines | HOFFMANN-LA ROCHE INC. | 2002-08-27 | — | — | US | disclosed |
| EP-0778264-B1 | Tertiary amines having antimycotic and cholesterol lowering activity | HOFFMANN LA ROCHE (CH) | 2001-07-11 | — | — | EP | disclosed |
| US-6034275-A | FUGICIDES; ATICHOLESTEROL AGENTS | HOFFMANN-LA ROCHE INC. (US) | 2000-03-07 | — | — | US | disclosed |
| CN-1158844-A | Tertiary amines | HOFFMANN LA ROCHE (CH) | 1997-09-10 | — | — | CN | disclosed |
| EP-0778264-A1 | Tertiary amines having antimycotic and cholesterol lowering activity | F. HOFFMANN-LA ROCHE AG (CH) | 1997-06-11 | — | — | EP | disclosed |