Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 5/20 | 0.40 |
| ▸ | CDK4 | P11802 | 3/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.35 |
| ▸ | ATR | Q13535 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7676795 | 0.89 | CDK2 (0.39) | CDK2CDK4CYP1A2CYP2C19MEN1 | |
| SCHEMBL7676510 | 0.89 | CDK2 (0.47) | CDK2CDK4CCNE1HPGDABCC9 | |
| SCHEMBL7682155 | 0.88 | CDK2 (0.40) | CDK2CDK4MEN1KMT2AHPGD | |
| SCHEMBL7681390 | 0.86 | CDK2 (0.46) | CDK2CDK4CCNE1ABCC9ABCC8 | |
| SCHEMBL7679500 | 0.86 | CDK2 (0.43) | CDK2CDK4ABCC9ABCC8KCNJ11 | |
| SCHEMBL7673991 | 0.85 | CDK2 (0.40) | CDK2CDK4CYP1A2CYP2D6CYP3A4 | |
| SCHEMBL7676916 | 0.85 | CDK2 (0.44) | CDK2CDK4CCNE1ABCC9ABCC8 | |
| SCHEMBL7676621 | 0.84 | CDK2 (0.43) | CDK2CDK4CCNE1ABCC9ABCC8 | |
| SCHEMBL7674349 | 0.84 | TRPV1 (0.40) | CDK2CDK4NTRK1 | |
| SCHEMBL7680020 | 0.84 | CDK2 (0.41) | CDK2CDK4CYP1A2CYP2C19NTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6358971-B1 | FOR INHIBITING THE GROWTH OF A PICORNAVIRUS | ELI LILLY AND COMPANY | 2002-03-19 | — | — | US | disclosed |