Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 3/20 | 0.41 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CCR1 | P32246 | 4/20 | 0.38 |
| ▸ | GRN | P28799 | 1/20 | 0.38 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 3/20 | 0.36 |
| ▸ | MMP9 | P14780 | 2/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | KISS1R | Q969F8 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4065205 | 0.88 | FFAR2 (0.37) | MMP1FFAR2LMNAMMP2MMP3 | |
| SCHEMBL7688310 | 0.87 | CCR1 (0.46) | MMP1CCR1MMP2MMP9MMP3 | |
| SCHEMBL4058890 | 0.77 | CCR1 (0.36) | MMP1LMNACCR1MMP2MMP9 | |
| SCHEMBL4065207 | 0.76 | CCR1 (0.45) | MMP1CCR1 | |
| SCHEMBL4063347 | 0.76 | CCR1 (0.37) | CCR1MMP2MMP3 | |
| SCHEMBL4063155 | 0.76 | SMN1; SMN2 (0.40) | ALDH1A1LMNACCR1 | |
| SCHEMBL4069707 | 0.74 | MMP3 (0.42) | MMP1ALDH1A1CCR1MMP2MMP9 | |
| SCHEMBL4065786 | 0.68 | MMP3 (0.36) | ALDH1A1LMNAMMP3 | |
| SCHEMBL4069086 | 0.67 | CTSD (0.42) | MMP1ALDH1A1MMP2MMP3 | |
| SCHEMBL4063159 | 0.66 | CCR1 (0.56) | CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403587-B1 | AUTOIMMUNE DISEASES, ACUTE AND CHRONIC INFLAMMATORY CONDITIONS, ALLERGIC CONDITIONS, INFECTION ASSOCIATED WITH INFLAMMATION, VIRAL, TRANSPLANTATION TISSUE REJECTION, ATHEROSCLEROSIS, RESTENOSIS, HIV INFECTIVITY, AND | PFIZER INC. | 2002-06-11 | — | — | US | disclosed |