Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.47 |
| ▸ | TMEM97 | Q5BJF2 | 4/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | HRH2 | P25021 | 2/20 | 0.44 |
| ▸ | HRH1 | P35367 | 2/20 | 0.44 |
| ▸ | HTR2C | P28335 | 2/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.44 |
| ▸ | HTR1B | P28222 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7675822 | 0.93 | P2RX7 (0.50) | P2RX7TMEM97SIGMAR1NOTUMCYP1A2 | |
| SCHEMBL7681311 | 0.88 | TSHR (0.55) | P2RX7NOTUMCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7682336 | 0.82 | P2RX7 (0.52) | P2RX7HTTL3MBTL1HTR2CHTR1A | |
| Hydrochloric Acid SCHEMBL7672600 | 0.81 | P2RX7 (0.51) | P2RX7HTTL3MBTL1HTR2CHTR1A | |
| SCHEMBL7678668 | 0.80 | P2RX7 (0.51) | P2RX7CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL14033021 | 0.80 | NOTUM (0.42) | NOTUMCYP1A2L3MBTL1 | |
| SCHEMBL7672812 | 0.78 | P2RX7 (0.56) | P2RX7SIGMAR1HRH1HTR2CHTR1A | |
| Hydrochloric Acid SCHEMBL7675560 | 0.77 | P2RX7 (0.55) | P2RX7SIGMAR1HRH1HTR2CHTR1A | |
| SCHEMBL7681242 | 0.77 | P2RX7 (0.55) | P2RX7SIGMAR1HTR2CHTR1ASLC6A3 | |
| Hydrochloric Acid SCHEMBL7673708 | 0.76 | P2RX7 (0.54) | P2RX7SIGMAR1HTR2CHTR1ASLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020151539-A1 | Novel heterocyclic compounds | JORGENSEN TINE KROGH (DK) | 2002-10-17 | — | — | US | disclosed |
| US-6391890-B1 | ANALGESICS, ANTIINFLAMMATORY AGENTS, NON-INSULIN DEPENDENT DIABETES | NOVO NORDISK A/S (DK) | 2002-05-21 | — | — | US | disclosed |
| US-6054458-A | Heterocyclic compounds | NOVONORDISKALS (DK) | 2000-04-25 | — | — | US | disclosed |
| EP-0991633-A1 | NOVEL HETEROCYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 2000-04-12 | — | — | EP | disclosed |
| WO-1999000376-A1 | NOVEL HETEROCYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 1999-01-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020151539-A1 | Novel heterocyclic compounds | IAPP, GPR119, NPY1R | P2RX7 68/4885TMEM97 1828/4885SIGMAR1 60/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.