Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.52 |
| ▸ | HTR2C | P28335 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.46 |
| ▸ | NCOR2 | Q9Y618 | 5/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7672600 | 0.99 | P2RX7 (0.51) | P2RX7HTR2CPOLBL3MBTL1KDM4E | |
| SCHEMBL7672812 | 0.92 | P2RX7 (0.56) | P2RX7HTR2CPOLBHDAC3HDAC1 | |
| Hydrochloric Acid SCHEMBL7675560 | 0.91 | P2RX7 (0.55) | P2RX7HTR2CHDAC3HDAC1HDAC8 | |
| SCHEMBL7681242 | 0.91 | P2RX7 (0.55) | P2RX7HTR2CHDAC3HDAC1HDAC8 | |
| Hydrochloric Acid SCHEMBL7673708 | 0.90 | P2RX7 (0.54) | P2RX7HTR2CHDAC3HDAC1HDAC8 | |
| SCHEMBL7682324 | 0.86 | ALDH1A1 (0.53) | P2RX7HTR2CPOLBL3MBTL1HDAC8 | |
| SCHEMBL7682340 | 0.82 | P2RX7 (0.47) | P2RX7HTR2CPOLBL3MBTL1HDAC1 | |
| SCHEMBL9468186 | 0.80 | P2RX7 (0.53) | P2RX7 | |
| SCHEMBL7678668 | 0.79 | P2RX7 (0.51) | P2RX7HTR2CHDAC3HDAC1HDAC8 | |
| SCHEMBL7675822 | 0.78 | P2RX7 (0.50) | P2RX7HTR2CPOLBL3MBTL1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020151539-A1 | Novel heterocyclic compounds | JORGENSEN TINE KROGH (DK) | 2002-10-17 | — | — | US | claimed |
| US-6054458-A | Heterocyclic compounds | NOVONORDISKALS (DK) | 2000-04-25 | — | — | US | claimed |
| EP-0991633-A1 | NOVEL HETEROCYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 2000-04-12 | — | — | EP | claimed |
| WO-1999000376-A1 | NOVEL HETEROCYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 1999-01-07 | — | — | WO | claimed |
| US-20020151539-A1 | Novel heterocyclic compounds | JORGENSEN TINE KROGH (DK) | 2002-10-17 | — | — | US | disclosed |
| US-6391890-B1 | ANALGESICS, ANTIINFLAMMATORY AGENTS, NON-INSULIN DEPENDENT DIABETES | NOVO NORDISK A/S (DK) | 2002-05-21 | — | — | US | disclosed |
| US-6054458-A | Heterocyclic compounds | NOVONORDISKALS (DK) | 2000-04-25 | — | — | US | disclosed |
| EP-0991633-A1 | NOVEL HETEROCYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 2000-04-12 | — | — | EP | disclosed |
| WO-1999000376-A1 | NOVEL HETEROCYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 1999-01-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020151539-A1 | Novel heterocyclic compounds | IAPP, GPR119, NPY1R | P2RX7 68/4885HTR2C 835/4885POLB 3313/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.