Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | ATM | Q13315 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.53 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | MAOA | P21397 | 2/20 | 0.51 |
| ▸ | IDO1 | P14902 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7682500 | 0.88 | POLB (0.60) | MEN1KMT2AATMPOLBKDM4E | |
| SCHEMBL7676641 | 0.86 | F12 (0.50) | MEN1KMT2AATMPOLBMAOA | |
| SCHEMBL7675773 | 0.85 | F2 (0.59) | POLB | |
| SCHEMBL7681946 | 0.84 | MEN1 (0.67) | MEN1KMT2AATMPOLBKDM4E | |
| SCHEMBL7681986 | 0.82 | POLB (0.47) | MEN1KMT2APOLBKDM4EALDH1A1 | |
| SCHEMBL7675721 | 0.82 | MEN1 (0.65) | MEN1KMT2AATMPOLBKDM4E | |
| SCHEMBL18752273 | 0.77 | MEN1 (0.56) | MEN1KMT2AATMPOLBHSP90AA1 | |
| SCHEMBL7679254 | 0.77 | F2 (0.68) | MEN1KMT2AATMPOLB | |
| SCHEMBL15733119 | 0.75 | MEN1 (0.72) | MEN1KMT2AATMPOLBKDM4E | |
| SCHEMBL7682335 | 0.74 | MAPT (0.58) | MEN1KMT2APOLBKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6355658-B1 | COUMARIN ESTERS WITH ETHER GROUPS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2002-03-12 | — | — | US | disclosed |