Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7680502 | 0.86 | TP53 (0.58) | ABCB11 | |
| SCHEMBL7680370 | 0.85 | ABCB11 (0.67) | ABCB11CCR2 | |
| SCHEMBL7675047 | 0.83 | TP53 (0.51) | ABCB11CCR2 | |
| SCHEMBL7673214 | 0.80 | ABCB11 (1.00) | ABCB11CCR2 | |
| SCHEMBL7683277 | 0.80 | ABCB11 (0.65) | ABCB11CCR2 | |
| SCHEMBL7682483 | 0.77 | CCR2 (0.58) | ABCB11CCR2 | |
| SCHEMBL6303320 | 0.77 | CCR2 (0.80) | ABCB11CCR2 | |
| SCHEMBL6303108 | 0.77 | CCR2 (0.79) | ABCB11CCR2 | |
| SCHEMBL3750485 | 0.76 | HSD17B10 (0.64) | — | |
| SCHEMBL7691746 | 0.76 | ABCB11 (1.00) | ABCB11CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6479527-B1 | Bicyclic pyrrole derivatives as MCP-1 inhibitors | ASTRAZENECA UK LIMITED (GB) | 2002-11-12 | — | — | US | disclosed |