Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13858739 | 0.87 | ALDH1A1 (0.53) | SRCALDH1A1CYP1A2CYP2C19MAPK1 | |
| SCHEMBL146965 | 0.83 | SRC (0.50) | SRCALDH1A1MAPK1KMT2AHSD17B10 | |
| SCHEMBL15516922 | 0.82 | MMP1 (0.48) | MMP1MMP9MMP8ALDH1A1KDM4E | |
| SCHEMBL2554336 | 0.82 | ALDH1A1 (0.54) | SRCALDH1A1MAPK1KMT2AMEN1 | |
| SCHEMBL2744258 | 0.82 | ALDH1A1 (0.59) | ALDH1A1CYP1A2CYP2C19MAPK1KDM4E | |
| SCHEMBL349748 | 0.81 | ALDH1A1 (0.58) | SRCALDH1A1CYP1A2CYP2C19MAPK1 | |
| SCHEMBL3681218 | 0.81 | HSP90AB1 (0.47) | MMP1MMP9MMP8ALDH1A1KDM4E | |
| SCHEMBL22379888 | 0.80 | KDM4E (0.41) | MMP1MMP9MMP8ALDH1A1CYP1A2 | |
| SCHEMBL2559847 | 0.80 | SRC (0.47) | SRCALDH1A1MAPK1KMT2AMEN1 | |
| SCHEMBL2281472 | 0.80 | ALDH1A1 (0.55) | ALDH1A1KDM4EMAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111285829-B | PPAR gamma/delta dual agonist, preparation method thereof and application thereof as medicament | 广东药科大学 | 2021-09-21 | — | — | CN | disclosed |
| WO-2021036514-A1 | PPAR γ/δ DUAL AGONIST, PREPARATION METHOD THEREOF AND USE THEREOF IN PREPARING A DRUG | 广东药科大学 | 2021-03-04 | — | — | WO | disclosed |
| WO-2021036514-A1 | PPAR γ/δ DUAL AGONIST, PREPARATION METHOD THEREOF AND USE THEREOF IN PREPARING A DRUG | 广东药科大学 | 2021-03-04 | — | — | WO | disclosed |
| CN-111285829-A | PPAR gamma/delta dual agonist, preparation method thereof and application thereof as medicament | 广东药科大学 | 2020-06-16 | — | — | CN | disclosed |
| US-6500853-B1 | ENZYME INHIBITORS SUCH AS 4-((1-BENZHYDRYL-5-(((BUTYLAMINO)-CARBONYL)AMINO)-1H-INDOL-3-YL)METHYL)-3 -METHOXYBENZOIC ACID USED AS ANTIINFLAMMATORY AGENTS FOR PROPHYLAXIS OF ARTHRITIS, INFLAMMATORY BOWEL DISEASE OR ASTHMA | GENETICS INSTITUTE, LLC | 2002-12-31 | — | — | US | disclosed |
| EP-1062205-A2 | INHIBITORS OF PHOSPHOLIPASE ENZYMES | GENETICS INSTITUTE, INC. (US) | 2000-12-27 | — | — | EP | disclosed |
| WO-1999043654-A2 | INHIBITORS OF PHOSPHOLIPASE ENZYMES | GENETICS INSTITUTE, INC. (US) | 1999-09-02 | — | — | WO | disclosed |