Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7954706 | 0.78 | ELANE (0.35) | TP53MDM2PTGDR2CA12CA2 | |
| SCHEMBL23518159 | 0.76 | CA9 (0.41) | TP53MDM2PTGDR2CA12CA2 | |
| SCHEMBL7686603 | 0.75 | GAA (0.35) | TP53MDM2PTGDR2CA12CA2 | |
| SCHEMBL12059117 | 0.67 | CA9 (0.40) | TP53CA12CA2CA9GAA | |
| SCHEMBL640001 | 0.65 | CA9 (0.35) | CA12CA2CA9GAAELANE | |
| SCHEMBL7686476 | 0.64 | GAA (0.35) | TP53CA12CA2CA9GAA | |
| SCHEMBL12041250 | 0.63 | CA9 (0.33) | CA12CA2CA9GAAELANE | |
| SCHEMBL30480962 | 0.63 | CA9 (0.33) | CA12CA2CA9GAAELANE | |
| SCHEMBL24132855 | 0.63 | CA9 (0.33) | CA12CA2CA9GAAELANE | |
| SCHEMBL26048155 | 0.63 | CA9 (0.33) | CA12CA2CA9GAAELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6346622-B1 | ENANTIOMORPHS AND ISOMERS | ABBOTT LABORATORIES | 2002-02-12 | — | — | US | disclosed |