Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 6/20 | 0.35 |
| ▸ | CA12 | O43570 | 5/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7679654 | 0.91 | GAA (0.37) | GAACA9CA12ELANETP53 | |
| SCHEMBL7954706 | 0.81 | ELANE (0.35) | GAACA9CA12ELANETP53 | |
| SCHEMBL7686603 | 0.73 | GAA (0.35) | GAACA9CA12ELANETP53 | |
| SCHEMBL7677803 | 0.70 | HTR7 (0.51) | — | |
| SCHEMBL23518159 | 0.69 | CA9 (0.41) | GAACA9CA12ELANETP53 | |
| SCHEMBL7686165 | 0.69 | HTR7 (0.54) | — | |
| SCHEMBL7677799 | 0.67 | CA2 (0.33) | GAACA9CA12ELANECA2 | |
| SCHEMBL24133108 | 0.65 | CA9 (0.39) | GAACA9CA12ELANETP53 | |
| SCHEMBL7683391 | 0.64 | TP53 (0.33) | GAACA9CA12ELANETP53 | |
| SCHEMBL6999953 | 0.63 | TDP1 (0.33) | ELANEALDH1A1TDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6346622-B1 | ENANTIOMORPHS AND ISOMERS | ABBOTT LABORATORIES | 2002-02-12 | — | — | US | disclosed |
| CN-1333685-A | Utilisation of I compound for the prophylaxis and therapy of cerebral ischaemia | BASF AG (DE) | 2002-01-30 | — | — | CN | disclosed |
| US-6300354-B1 | FOR THERAPY OF NEUROLEPTIC DISEASES | BASF AKTIENGESELLSCHAFT (DE) | 2001-10-09 | — | — | US | disclosed |
| CN-1312809-A | N-substituted azabicycloheptane deriratives, production and use thereof | BASF AG (DE) | 2001-09-12 | — | — | CN | disclosed |
| CN-1277607-A | 2-substituted 1,2-benzisothiazole derivatives and their use as serotonin antagonists (5-HT1A, 5-HT1b and 5-HT1D) | BASF AG (DE) | 2000-12-20 | — | — | CN | disclosed |