Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 8/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 7/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7686603 | 0.91 | GAA (0.35) | ELANECA9CA2GAACA12 | |
| SCHEMBL23518159 | 0.81 | CA9 (0.41) | ELANECA9CA2GAACA12 | |
| SCHEMBL7686476 | 0.81 | GAA (0.35) | ELANECA9CA2GAACA12 | |
| SCHEMBL7677799 | 0.78 | CA2 (0.33) | ELANECA9CA2GAACA12 | |
| SCHEMBL7683391 | 0.78 | TP53 (0.33) | ELANECA9CA2GAACA12 | |
| SCHEMBL7954891 | 0.76 | RAB9A (0.40) | CA9CA12ALDH1A1KMT2AMEN1 | |
| SCHEMBL12059117 | 0.75 | CA9 (0.40) | CA9CA2GAACA12TP53 | |
| SCHEMBL7679654 | 0.73 | GAA (0.37) | ELANECA9CA2GAACA12 | |
| SCHEMBL640001 | 0.70 | CA9 (0.35) | ELANECA9CA2GAACA12 | |
| SCHEMBL7685522 | 0.69 | HTR7 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300354-B1 | FOR THERAPY OF NEUROLEPTIC DISEASES | BASF AKTIENGESELLSCHAFT (DE) | 2001-10-09 | — | — | US | disclosed |
| CN-1312809-A | N-substituted azabicycloheptane deriratives, production and use thereof | BASF AG (DE) | 2001-09-12 | — | — | CN | disclosed |