Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 6/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.48 |
| ▸ | HTR6 | P50406 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.44 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6272803 | 0.83 | MTNR1B (0.50) | MTNR1AMTNR1BHTR6FFAR1PRMT5 | |
| SCHEMBL14356155 | 0.83 | MTNR1B (0.50) | MTNR1AMTNR1BHTR6FFAR1PRMT5 | |
| SCHEMBL7847075 | 0.81 | FFAR1 (0.62) | MTNR1AMTNR1BHTR6FFAR1PRMT5 | |
| SCHEMBL7845908 | 0.81 | FFAR1 (0.62) | MTNR1AMTNR1BHTR6FFAR1PRMT5 | |
| SCHEMBL1470461 | 0.81 | FFAR1 (0.62) | MTNR1AMTNR1BHTR6FFAR1PRMT5 | |
| SCHEMBL1567606 | 0.81 | MTNR1A (0.51) | MTNR1AMTNR1BHTR6FFAR1PRMT5 | |
| SCHEMBL3348647 | 0.80 | CYP1A2 (0.47) | MTNR1AMTNR1BHTR6FFAR1PRMT5 | |
| SCHEMBL30618514 | 0.80 | CYP1A2 (0.47) | MTNR1AMTNR1BHTR6FFAR1PRMT5 | |
| SCHEMBL4714587 | 0.80 | HTR6 (0.51) | MTNR1AMTNR1BHTR6FFAR1PRMT5 | |
| SCHEMBL7296740 | 0.80 | MTNR1A (0.50) | MTNR1AMTNR1BHTR6FFAR1PRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6362141-B1 | ORGANOLEPTIC; PERFUMES, COSMETICS, CLEANING COMPOUNDS | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2002-03-26 | — | — | US | disclosed |
| US-6342612-B1 | FRAGRANCES | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2002-01-29 | — | — | US | disclosed |