Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.35 |
| ▸ | TYK2 | P29597 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8218958 | 0.85 | KMT2A (0.43) | ACLYKMT2AL3MBTL1POLBTSHR | |
| SCHEMBL7682908 | 0.80 | KEAP1 (0.42) | ACLYKMT2ALMNAL3MBTL1POLB | |
| SCHEMBL7558061 | 0.75 | CSNK2A1 (0.44) | ACLYKMT2AL3MBTL1POLBTSHR | |
| SCHEMBL19084967 | 0.75 | CSNK2A1 (0.49) | KMT2AL3MBTL1POLBTSHRALDH1A1 | |
| SCHEMBL6646574 | 0.75 | KMT2A (0.43) | KMT2AL3MBTL1POLBTSHRUSP2 | |
| SCHEMBL7556650 | 0.73 | TSHR (0.49) | ACLYKMT2ALMNATSHRALDH1A1 | |
| SCHEMBL7689156 | 0.73 | C5AR1 (0.49) | ACLYKMT2ALMNATSHRALDH1A1 | |
| SCHEMBL30005614 | 0.73 | KMT2A (0.45) | KMT2AL3MBTL1POLBTSHRCYP19A1 | |
| SCHEMBL7558164 | 0.73 | KMT2A (0.42) | KMT2ALMNAL3MBTL1POLBTSHR | |
| SCHEMBL7684663 | 0.73 | LMNA (0.53) | KMT2ALMNAL3MBTL1POLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020045551-A1 | 4-benzoyl isoxazoles derivatives and their use as herbicides | MUSIL TIBOR (GB) | 2002-04-18 | — | — | US | disclosed |
| CN-1082790-C | Herbicides | RHONE POULENE AGRICULTURE LTD (GB) | 2002-04-17 | — | — | CN | disclosed |
| US-6323155-B1 | EXCELLENT LEVEL OF HERBICIDAL ACTIVITY TOGETHER WITH CROP TOLERANCE | RHONE-POULENC AGRICULTURE LIMITED (GB) | 2001-11-27 | — | — | US | disclosed |
| EP-0811611-B1 | 2-cyano-1-sulfonamidophenyl-1,3-dione derivatives and their use as herbicides | RHONE POULENC AGRICULTURE (GB) | 2000-01-26 | — | — | EP | disclosed |
| EP-0674629-B1 | 4-BENZOYL ISOXAZOLES DERIVATIVES AND THEIR USE AS HERBICIDES | RHONE POULENC AGRICULTURE (GB) | 1998-07-08 | — | — | EP | disclosed |
| EP-0811611-A1 | 2-cyano-1-sulfonamidophenyl-1,3-dione derivatives and their use as herbicides | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-12-10 | — | — | EP | disclosed |
| EP-0674629-A1 | 4-BENZOYL ISOXAZOLES DERIVATIVES AND THEIR USE AS HERBICIDES | RHONE-POULENC AGRICULTURE LTD. (GB) | 1995-10-04 | — | — | EP | disclosed |
| EP-0625505-A2 | 2-Cyano-1,3-dione derivatives and their use as herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1994-11-23 | — | — | EP | disclosed |
| WO-1994014782-A1 | 4-BENZOYL ISOXAZOLES DERIVATIVES AND THEIR USE AS HERBICIDES | RHONE-POULENC AGRICULTURE LTD. (GB) | 1994-07-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020045551-A1 | 4-benzoyl isoxazoles derivatives and their use as herbicides | CBR3, CBR1, GLRA3 | ACLY 611/4885KMT2A 3499/4885LMNA 2378/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.