Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PGK1 | P00558 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.34 |
| ▸ | WNT3A | P56704 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27033280 | 0.83 | DYRK1A (0.43) | ALDH1A1CHRNB2CHRNA4MEN1GAA | |
| SCHEMBL10943939 | 0.83 | CHRNB2 (0.42) | ALDH1A1CHRNB2CHRNA4MEN1GAA | |
| SCHEMBL5084517 | 0.76 | CHRNB2 (0.38) | HSD17B10ALDH1A1CHRNB2CHRNA4MEN1 | |
| SCHEMBL1701091 | 0.76 | AHR (0.39) | ALDH1A1CHRNB2CHRNA4MEN1GAA | |
| SCHEMBL941915 | 0.75 | CHRNB2 (0.48) | ALDH1A1CHRNB2CHRNA4MEN1GAA | |
| SCHEMBL9118160 | 0.73 | TRPM5 (0.37) | ALDH1A1CHRNB2CHRNA4MEN1GAA | |
| SCHEMBL6119475 | 0.73 | CHRNB2 (0.47) | ALDH1A1CHRNB2CHRNA4MEN1GAA | |
| SCHEMBL4567566 | 0.72 | DYRK1A (0.42) | HSD17B10ALDH1A1CHRNB2CHRNA4MEN1 | |
| SCHEMBL8861572 | 0.72 | CHRNB2 (0.38) | HSD17B10ALDH1A1CHRNB2CHRNA4MEN1 | |
| SCHEMBL24984323 | 0.72 | CHRNB2 (0.35) | ALDH1A1CHRNB2CHRNA4MEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2002539450-A | — | — | 2002-11-19 | — | — | JP | claimed |
| EP-1163518-A2 | ELISA KIT FOR THE DETERMINATION OF METABOLIC PHENOTYPES | Leyland-Jones, Brian (CA) | 2001-12-19 | — | — | EP | claimed |
| WO-2000055624-A2 | ELISA KIT FOR THE DETERMINATION OF METABOLIC PHENOTYPES | LEYLAND JONES BRIAN (CA) | 2000-09-21 | — | — | WO | claimed |