SCHEMBL6119475

SCHEMBL6119475

c1nc2cc3ncoc3cc2o1

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 1/20 0.47
CHRNA4 P43681 1/20 0.47
DYRK1A Q13627 2/20 0.44
MEN1 O00255 1/20 0.42
ALDH1A1 P00352 1/20 0.42
GAA P10253 1/20 0.42
KMT2A Q03164 1/20 0.42
CTNNB1 P35222 4/20 0.38
WNT3A P56704 4/20 0.38
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
LMNA P02545 1/20 0.36
TAS1R3 Q7RTX0 1/20 0.33
TAS1R1 Q7RTX1 1/20 0.33
NAMPT P43490 2/20 0.33
TRPM5 Q9NZQ8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL941915 0.91 CHRNB2 (0.48) CHRNB2CHRNA4DYRK1AMEN1ALDH1A1
SCHEMBL19269012 0.81 DYRK1A (0.41) CHRNB2CHRNA4DYRK1AMEN1ALDH1A1
SCHEMBL27033280 0.79 DYRK1A (0.43) CHRNB2CHRNA4DYRK1AMEN1ALDH1A1
SCHEMBL10943939 0.79 CHRNB2 (0.42) CHRNB2CHRNA4DYRK1AMEN1ALDH1A1
SCHEMBL927293 0.79 CHRNB2 (0.42) CHRNB2CHRNA4DYRK1AMEN1ALDH1A1
SCHEMBL20274105 0.79 CHRNB2 (0.42) CHRNB2CHRNA4DYRK1AMEN1ALDH1A1
SCHEMBL29888711 0.79 CHRNB2 (0.42) CHRNB2CHRNA4DYRK1AMEN1ALDH1A1
SCHEMBL26502149 0.79 L3MBTL1 (0.41) CHRNB2CHRNA4DYRK1AMEN1ALDH1A1
SCHEMBL4137615 0.78 CYP2A6 (0.43) CHRNB2CHRNA4DYRK1AMEN1ALDH1A1
SCHEMBL1156058 0.76 NQO2 (0.50) CHRNB2CHRNA4DYRK1AMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0145337-B1 ELECTROCHROMIC DEVICES CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) 1990-08-08 EP claimed
EP-0096723-B1 BATTERIES FABRICATED WITH ELECTROACTIVE POLYMERS CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) 1988-08-10 EP claimed
US-4613211-A REVERSE COLOR CHANGING POLYMER FILM AS DISPLAY ELECTRODE CHEVRON RESEARCH COMPANY (US) 1986-09-23 US claimed
US-4522745-A NITROGEN CONTAINING RING;POSSIBLY CONTAINING OXYGEN, SULFUR, SELENIUM OR TELLURIUM CHEVRON RESEARCH COMPANY (US) 1985-06-11 US claimed
WO-2023249053-A1 METHOD FOR PRODUCING FILM 東洋紡株式会社 2023-12-28 WO disclosed
WO-2023243693-A1 LAMINATE 東洋紡株式会社 2023-12-21 WO disclosed
WO-2023189719-A1 LAMINATE AND METHOD FOR PRODUCING LAMINATE 東洋紡株式会社 2023-10-05 WO disclosed
WO-2023178136-A2 STRETCHABLE LIGHT-EMITTING POLYMERS THE UNIVERSITY OF CHICAGO (US) 2023-09-21 WO disclosed
US-20230036119-A1 QUANTUM DOTS WITH DONOR-ACCEPTOR LIGANDS NANOSYS, INC. 2023-02-02 US disclosed
US-20210202864-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT KYULUX, INC. (JP) 2021-07-01 US disclosed
WO-2020039708-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT 国立大学法人九州大学 2020-02-27 WO disclosed
US-20180212158-A1 ORGANIC LIGHT-EMITTING DIODE MATERIALS PRESIDENT AND FELLOWS OF HARVARD COLLEGE 2018-07-26 US disclosed
EP-0096723-B1 BATTERIES FABRICATED WITH ELECTROACTIVE POLYMERS CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) 1988-08-10 EP disclosed
US-4613211-A REVERSE COLOR CHANGING POLYMER FILM AS DISPLAY ELECTRODE CHEVRON RESEARCH COMPANY (US) 1986-09-23 US disclosed
EP-0126064-A4 ELECTROACTIVE POLYMERS. CHEVRON RES (US) 1985-07-01 EP disclosed
EP-0145337-A2 Electrochromic devices CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) 1985-06-19 EP disclosed
US-4522745-A NITROGEN CONTAINING RING;POSSIBLY CONTAINING OXYGEN, SULFUR, SELENIUM OR TELLURIUM CHEVRON RESEARCH COMPANY (US) 1985-06-11 US disclosed
EP-0126064-A1 ELECTROACTIVE POLYMERS CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) 1984-11-28 EP disclosed
WO-1984002030-A1 ELECTROACTIVE POLYMERS CHEVRON RES (US) 1984-05-24 WO disclosed
US-4108835-A Phenylated aromatic heterocyclic polymers THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 1978-08-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180212158-A1 ORGANIC LIGHT-EMITTING DIODE MATERIALS MSN, DDT, NECTIN4 CHRNB2 3415/4885CHRNA4 3819/4885DYRK1A 2428/4885
US-20210202864-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT LEF1, EMC1, EEA1 CHRNB2 1851/4885CHRNA4 1828/4885DYRK1A 4124/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.