Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.54 |
| ▸ | CA2 | P00918 | 3/20 | 0.54 |
| ▸ | CA12 | O43570 | 2/20 | 0.54 |
| ▸ | CA9 | Q16790 | 2/20 | 0.54 |
| ▸ | ATAD2 | Q6PL18 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | GSTO1 | P78417 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7628615 | 0.88 | CA12 (0.52) | CA1CA2CA12CA9ATAD2 | |
| SCHEMBL7637211 | 0.85 | CA2 (0.50) | CA1CA2CA12CA9ATAD2 | |
| SCHEMBL7679850 | 0.85 | ATM (0.43) | CA1CA2CA12CA9ATAD2 | |
| SCHEMBL7686850 | 0.83 | CDK1 (0.43) | CA1CA2CA12CA9GSTO1 | |
| SCHEMBL7628690 | 0.78 | CDK1 (0.54) | CA1CA2CA12CA9GSTO1 | |
| SCHEMBL7632558 | 0.76 | POLB (0.48) | CA1CA2CA12CA9ATM | |
| SCHEMBL6104098 | 0.75 | ALDH1A1 (0.42) | CA1CA2CA12CA9ATM | |
| SCHEMBL11375617 | 0.75 | CYP3A4 (0.65) | CA1CA2CA12CA9ATAD2 | |
| SCHEMBL6107089 | 0.73 | CDK1 (0.75) | GSTO1MAPTCYP1A2KMT2A | |
| SCHEMBL2979899 | 0.73 | CDK1 (0.74) | ATMPOLBMAPTMEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6498253-B1 | Acylated aminophenylsulfonylureas, processes for their preparation and their use as herbicides and plant growth regulators | HOECHST SCHERING AGREVO GMBH (DE) | 2002-12-24 | — | — | US | disclosed |
| CN-1066140-C | Acylated aminophenylsulfonylureas, processes for their preparation and their use as herbicides and plant growth regulators | HOECHST SCHERING AGREVO GMBH (DE) | 2001-05-23 | — | — | CN | disclosed |
| US-5922646-A | PRE-EMERGENCE AND POST-EMERGENCE HERBICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 1999-07-13 | — | — | US | disclosed |
| EP-0757679-B1 | ACYLATED AMINOPHENYLSULPHONYLUREAS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES AND PLANT-GROWTH REGULATORS | HOECHST SCHERING AGREVO GMBH (DE) | 1998-10-21 | — | — | EP | disclosed |
| EP-0757679-A1 | ACYLATED AMINOPHENYLSULPHONYLUREAS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES AND PLANT-GROWTH REGULATORS | Hoechst Schering AgrEvo GmbH (DE) | 1997-02-12 | — | — | EP | disclosed |
| WO-1995029899-A1 | ACYLATED AMINOPHENYLSULPHONYLUREAS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES AND PLANT-GROWTH REGULATORS | HOECHST SCHERING AGREVO GMBH (DE) | 1995-11-09 | — | — | WO | disclosed |