SCHEMBL768377

SCHEMBL768377

CCCc1ccc(-c2ccc(-c3cc(F)c(F)c(F)c3)c(F)c2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RARB P10826 3/20 0.45
RARA P10276 1/20 0.44
RARG P13631 1/20 0.44
MCL1 Q07820 1/20 0.42
TAAR1 Q96RJ0 1/20 0.39
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
TP53 P04637 1/20 0.38
PKM P14618 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
HSD17B10 Q99714 1/20 0.38
MAOB P27338 1/20 0.37
CNR1 P21554 1/20 0.37
CNR2 P34972 1/20 0.37
ALOX5 P09917 1/20 0.36
MAPT P10636 1/20 0.36
GFER P55789 1/20 0.36
CYP17A1 P05093 2/20 0.36
CYP11B1 P15538 1/20 0.36
CYP11B2 P19099 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12566384 1.00 RARB (0.45) RARBRARARARGMCL1TAAR1
SCHEMBL29758266 1.00 RARB (0.45) RARBRARARARGMCL1TAAR1
SCHEMBL16258025 0.98 RARB (0.44) RARBRARARARGMCL1TAAR1
SCHEMBL16257979 0.94 RARB (0.41) RARBRARARARGMCL1TAAR1
SCHEMBL9512294 0.91 RARB (0.51) RARBRARARARGMCL1TAAR1
SCHEMBL10603849 0.91 RARB (0.51) RARBRARARARGMCL1TAAR1
SCHEMBL15433162 0.90 RARB (0.52) RARBRARARARGHSD17B10MAPT
SCHEMBL13239278 0.90 RARB (0.52) RARBRARARARGHSD17B10MAPT
SCHEMBL7183626 0.90 RARB (0.42) RARBRARARARGNPC1RAB9A
SCHEMBL16258065 0.90 CNR1 (0.43) RARBRARARARGNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 394 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250011590-A1 OPTICAL FILM AND POLARIZING PLATE TOSOH CORPORATION (JP) 2025-01-09 US disclosed
US-12043783-B2 Liquid crystal composition containing benzochromene compound and use thereof SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO., LTD. (CN) 2024-07-23 US disclosed
US-12043783-B2 Liquid crystal composition containing benzochromene compound and use thereof SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO., LTD. (CN) 2024-07-23 US disclosed
US-20240239934-A1 FUMARIC ACID DIESTER RESIN, FILM AND POLARIZING PLATE TOSOH CORPORATION (JP) 2024-07-18 US disclosed
CN-118235072-A Optical film and polarizing plate 东曹株式会社 2024-06-21 CN disclosed
EP-4299283-A1 FUMARIC ACID DIESTER RESIN, FILM AND POLARIZING PLATE Tosoh Corporation (JP) 2024-01-03 EP disclosed
US-20230167363-A1 LIQUID CRYSTAL COMPOSITION CONTAINING BENZOCHROMENE COMPOUND AND USE THEREOF SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO.,LTD. (CN) 2023-06-01 US disclosed
US-20230167363-A1 LIQUID CRYSTAL COMPOSITION CONTAINING BENZOCHROMENE COMPOUND AND USE THEREOF SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO.,LTD. (CN) 2023-06-01 US disclosed
US-11560517-B2 Photoreactive liquid crystal composition, display element, optical element, method for manufacturing display element, and method for manufacturing optical element UNIVERSITY OF HYOGO (JP) 2023-01-24 US disclosed
WO-2022210589-A1 FUMARIC ACID DIESTER RESIN, FILM AND POLARIZING PLATE 東ソー株式会社 2022-10-06 WO disclosed
US-20100294991-A1 Liquid Crystal Composition and Liquid Crystal Display Device CHISSO CORPORATION (JP) 2010-11-25 US disclosed
US-20100272927-A1 Liquid Crystal Composition and Liquid Crystal Display Device CHISSO CORPORATION (JP) 2010-10-28 US disclosed
US-20100272927-A1 Liquid Crystal Composition and Liquid Crystal Display Device CHISSO CORPORATION (JP) 2010-10-28 US disclosed
US-20100272926-A1 Liquid Crystal Composition and Liquid Crystal Display Device CHISSO CORPORATION (JP) 2010-10-28 US disclosed
US-20100272926-A1 Liquid Crystal Composition and Liquid Crystal Display Device CHISSO CORPORATION (JP) 2010-10-28 US disclosed
US-20100243957-A1 Liquid Crystal Composition and Liquid Crystal Display Device CHISSO CORPORATION (JP) 2010-09-30 US disclosed
US-20100243957-A1 Liquid Crystal Composition and Liquid Crystal Display Device CHISSO CORPORATION (JP) 2010-09-30 US disclosed
US-20100073621-A1 LIQUID CRYSTALLINE COMPOUND, LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL DISPLAY ELEMENT CHISSO CORPORATION (JP) 2010-03-25 US disclosed
US-20100073621-A1 LIQUID CRYSTALLINE COMPOUND, LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL DISPLAY ELEMENT CHISSO CORPORATION (JP) 2010-03-25 US disclosed
EP-2123623-A1 LIQUID CRYSTALLINE COMPOUND, LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL DISPLAY ELEMENT Chisso Corporation (JP) 2009-11-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100073621-A1 LIQUID CRYSTALLINE COMPOUND, LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL DISPLAY ELEMENT TRPV4, TRPV5, ZKSCAN2 RARB 2425/4885RARA 2650/4885RARG 3171/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.