Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 4/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
| ▸ | PAM | P19021 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3783785 | 0.82 | RELA (0.43) | EGFRALOX15HSD17B10ALDH1A1CYP2C19 | |
| SCHEMBL27414917 | 0.72 | HAO1 (0.44) | EGFRHAO1ALDH1A1HDAC3PAM | |
| Itaconate SCHEMBL11309982 | 0.72 | MEN1 (0.48) | EGFRHAO1ALDH1A1HDAC3CTDSP1 | |
| Itaconate SCHEMBL3201278 | 0.71 | ALOX15 (0.57) | ALOX15HSD17B10HAO1ALDH1A1HDAC3 | |
| Juarezic Acid SCHEMBL8768055 | 0.70 | HDAC3 (0.53) | ALOX15HSD17B10HAO1ALDH1A1HDAC3 | |
| Itaconate SCHEMBL6053436 | 0.70 | ALOX15 (0.47) | ALOX15HSD17B10HAO1ALDH1A1HDAC3 | |
| SCHEMBL9128813 | 0.70 | CYP2C19 (0.41) | EGFRALDH1A1HDAC3CTDSP1PAM | |
| Itaconate SCHEMBL7058781 | 0.69 | ALOX15 (0.44) | ALOX15HSD17B10ALDH1A1RECQLCYP2C19 | |
| SCHEMBL8401214 | 0.69 | PPARA (0.43) | EGFRHAO1ALDH1A1HDAC3CTDSP1 | |
| Itaconate SCHEMBL11140941 | 0.68 | ALOX15 (0.42) | ALOX15HSD17B10HAO1ALDH1A1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6395367-B1 | ELECTROCONDUCTIVITY | HYDRO-QUEBEC (CA) | 2002-05-28 | — | — | US | claimed |