Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 7/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LDHA | P00338 | 2/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | PTGES | O14684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7688469 | 0.82 | CCR2 (0.56) | CCR2ALDH1A1KDM4EPSEN1PSEN2 | |
| SCHEMBL699773 | 0.81 | CCR2 (0.63) | CCR2ALDH1A1KDM4ELDHAPTGDR2 | |
| SCHEMBL3958982 | 0.78 | CCR2 (0.56) | CCR2ALDH1A1KDM4EKMT2AMCL1 | |
| SCHEMBL7681815 | 0.75 | CCR2 (0.55) | CCR2PTGDR2NTRK1 | |
| SCHEMBL27308876 | 0.74 | CCR2 (0.55) | CCR2ALDH1A1LDHAKMT2AMCL1 | |
| SCHEMBL7682122 | 0.74 | CCR2 (0.40) | CCR2ALDH1A1KDM4EKMT2A | |
| SCHEMBL29812990 | 0.74 | CCR2 (0.54) | CCR2ALDH1A1KDM4ELDHAMCL1 | |
| SCHEMBL8347 | 0.73 | LDHA (0.66) | CCR2LDHA | |
| SCHEMBL14643991 | 0.73 | NTRK1 (0.55) | CCR2ALDH1A1KDM4EPSEN1PSEN2 | |
| SCHEMBL15762231 | 0.73 | NTRK1 (0.57) | ALDH1A1KDM4EPTGDR2NTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6380230-B1 | FOR THERAPY OF DYSKINESIA, OBESITY, IRRITABLE BOWEL SYNDROME, DISEASES WHOSE TREATMENT REQUIRES STIMULATION OF THE CHOLECYSTOKININ CCK-A RECEPTORS | SANOFI-SYNTHELABO (FR) | 2002-04-30 | — | — | US | disclosed |