Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 8/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 7/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
| ▸ | JAK3 | P52333 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.39 |
| ▸ | FABP4 | P15090 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7683717 | 0.85 | SMN1; SMN2 (0.46) | CCR2KDM4EALDH1A1MTNR1BMTNR1A | |
| SCHEMBL7682122 | 0.85 | CCR2 (0.40) | CCR2KDM4EALDH1A1MTNR1BMTNR1A | |
| SCHEMBL7683902 | 0.82 | CCR2 (0.55) | CCR2KDM4EALDH1A1PSEN1PSEN2 | |
| SCHEMBL699964 | 0.81 | CCR2 (0.65) | CCR2KDM4EALDH1A1MTNR1BMTNR1A | |
| SCHEMBL3958982 | 0.79 | CCR2 (0.56) | CCR2KDM4EALDH1A1MCL1 | |
| SCHEMBL15764624 | 0.78 | NTRK1 (0.60) | CCR2KDM4EALDH1A1HSD17B10 | |
| SCHEMBL30622480 | 0.78 | CCR2 (0.61) | CCR2KDM4EALDH1A1MTNR1BMTNR1A | |
| SCHEMBL7006463 | 0.77 | CCR2 (0.60) | CCR2KDM4EALDH1A1MTNR1BMTNR1A | |
| SCHEMBL29035005 | 0.76 | CCR2 (0.52) | CCR2KDM4EALDH1A1MTNR1BMTNR1A | |
| SCHEMBL14643991 | 0.76 | NTRK1 (0.55) | CCR2KDM4EALDH1A1PSEN1PSEN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6380230-B1 | FOR THERAPY OF DYSKINESIA, OBESITY, IRRITABLE BOWEL SYNDROME, DISEASES WHOSE TREATMENT REQUIRES STIMULATION OF THE CHOLECYSTOKININ CCK-A RECEPTORS | SANOFI-SYNTHELABO (FR) | 2002-04-30 | — | — | US | disclosed |