Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GGPS1 | O95749 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | FDPS | P14324 | 10/20 | 0.45 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7687673 | 1.00 | GGPS1 (0.48) | GGPS1ALDH1A1TSHRFDPSSMPD1 | |
| SCHEMBL7684614 | 1.00 | GGPS1 (0.48) | GGPS1ALDH1A1TSHRFDPSSMPD1 | |
| SCHEMBL7679775 | 0.98 | GGPS1 (0.45) | GGPS1ALDH1A1TSHRFDPSSMPD1 | |
| SCHEMBL9015656 | 0.83 | GGPS1 (0.45) | GGPS1ALDH1A1TSHRFDPSSMPD1 | |
| SCHEMBL9015600 | 0.83 | GGPS1 (0.45) | GGPS1ALDH1A1TSHRFDPSSMPD1 | |
| SCHEMBL9015662 | 0.83 | GGPS1 (0.45) | GGPS1ALDH1A1TSHRFDPSSMPD1 | |
| SCHEMBL25078902 | 0.82 | ALDH1A1 (0.48) | GGPS1ALDH1A1TSHRFDPSSMPD1 | |
| SCHEMBL8648600 | 0.82 | ALDH1A1 (0.48) | GGPS1ALDH1A1TSHRFDPSSMPD1 | |
| SCHEMBL25303536 | 0.82 | ALDH1A1 (0.48) | GGPS1ALDH1A1TSHRFDPSSMPD1 | |
| SCHEMBL10830500 | 0.82 | ALDH1A1 (0.48) | GGPS1ALDH1A1TSHRFDPSSMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5047563-A | Ionophores | MILES INC. (US) | 1991-09-10 | — | — | US | claimed |
| EP-0306802-B1 | CHIRAL CROWN ETHERS | MILES INC. (US) | 1991-05-15 | — | — | EP | claimed |
| EP-0306802-A1 | Chiral crown ethers | MILES INC. (US) | 1989-03-15 | — | — | EP | claimed |
| US-20020028970-A1 | SYNTHESIS OF A TETRAAMIDO MACROCYCLE LIGAND FROM A NOVEL DIAMIDODIOL | THE CLOROX COMPANY | 2002-03-07 | — | — | US | disclosed |
| WO-2001002343-A1 | IMPROVED SYNTHESIS OF A TETRAAMIDO MACROCYCLE LIGAND FROM A NOVEL DIAMIDODIOL | THE CLOROX COMPANY (US) | 2001-01-11 | — | — | WO | disclosed |
| US-5133934-A | Enantiomorphs of bis/12-crown-4-methyl/ dialkyl malonate, a carrier and ionophore | MILES INC. (US) | 1992-07-28 | — | — | US | disclosed |
| US-5047563-A | Ionophores | MILES INC. (US) | 1991-09-10 | — | — | US | disclosed |
| EP-0306802-B1 | CHIRAL CROWN ETHERS | MILES INC. (US) | 1991-05-15 | — | — | EP | disclosed |
| EP-0306802-A1 | Chiral crown ethers | MILES INC. (US) | 1989-03-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020028970-A1 | SYNTHESIS OF A TETRAAMIDO MACROCYCLE LIGAND FROM A NOVEL DIAMIDODIOL | DDT, DDC, MLYCD | GGPS1 2284/4885ALDH1A1 370/4885TSHR 1922/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.